Protein Alignment cocoon and NUC-L1

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_175322.1
• Gene: NUC-L1 / 841314
• AraportID: AT1G48920
• Length: 557
• Species: Arabidopsis thaliana
• Alignment Length: 250
• Identity: 62/250 - (24%)
• Similarity: 93/250 - (37%)
• Gaps: 63/250 - (25%)

  Fly     7 SEKEGDEPI--ELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGW 69
            |:::.||..  |.||:                      :..||||.:...|:|.   |.|||...
plant   219 SDEDSDEESEDEKPAQ----------------------KKADTKASKKSSSDES---SESEEDES 258

  Fly    70 GEYHYFCVFPKKNKRQSED----NLENSTA---KTKRTEAHLRCFDLIVLGLSYNTTEQDLREYF 127
            .:..      :..|::|.|    :.|.|:|   ||..|.|......|....||:|....|:..:|
plant   259 EDEE------ETPKKKSSDVEMVDAEKSSAKQPKTPSTPAAGGSKTLFAANLSFNIERADVENFF 317

  Fly   128 ETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLS-KRHSIDGRWCEVKVPASRGMGNQEP 191
            :..|:||......:...|..:|||.|.|.|.:.....|. ....:.||...:.:...||...:.|
plant   318 KEAGEVVDVRFSTNRDDGSFRGFGHVEFASSEEAQKALEFHGRPLLGREIRLDIAQERGERGERP 382

  Fly   192 G------------------KVFVGRCTEDIEADD----LREYFSKFGEVIDVFIP 224
            .                  |:||......:..||    |||:||..||:.:|.:|
plant   383 AFTPQSGNFRSGGDGGDEKKIFVKGFDASLSEDDIKNTLREHFSSCGEIKNVSVP 437

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	16/72 (22%)
		RRM1_TDP43	108..181	CDD:409760	19/73 (26%)
		RRM2_TDP43	193..262	CDD:409761	13/35 (37%)
NUC-L1	NP_175322.1	RRM1_NUCLs	298..375	CDD:409884	19/76 (25%)
		RRM2_NUCLs	402..479	CDD:409885	13/35 (37%)