Protein Alignment cocoon and NUC-L2

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_188491.1
• Gene: NUC-L2 / 821392
• AraportID: AT3G18610
• Length: 636
• Species: Arabidopsis thaliana
• Alignment Length: 280
• Identity: 67/280 - (23%)
• Similarity: 103/280 - (36%)
• Gaps: 54/280 - (19%)

  Fly     7 SEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGE 71
            ||::.||      ||.......|.:|:....:..|..:.|..      |:|.......:|.
plant   300 SEEDSDE------EESDDEKPPTKKAKVSSKTSKQESSSDES------SDESDKEESKDEK---- 348

  Fly    72 YHYFCVFPKKNKRQSE--DNLENSTAK-----TKRTEAHLRCFDLIVLGLSYNTTEQDLREYFET 129
                 |.|||.....|  |..:.|.||     |.:|:...:  .|....|||.....|:..:|:.
plant   349 -----VTPKKKDSDVEMVDAEQKSNAKQPKTPTNQTQGGSK--TLFAGNLSYQIARSDIENFFKE 406

  Fly   130 YGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHS-IDGRWCEVKVPASRGM-GNQEPG 192
            .|:||...: .....|..||:|.:.|.|.:.....|..... :.||...:.:...||. .|..||
plant   407 AGEVVDVRL-SSFDDGSFKGYGHIEFASPEEAQKALEMNGKLLLGRDVRLDLANERGTPRNSNPG 470

  Fly   193 KV-------------FVGRCTEDIEADDLREYFSKFGEVIDVFIPK-----PFRAFSFVTFLDPY 239
            :.             |.....||....:||.:|||.|||..|.:|.     ..|.|:::.....:
plant   471 RKGEGSQSRTIYVRGFSSSLGEDEIKKELRSHFSKCGEVTRVHVPTDRETGASRGFAYIDLTSGF 535

  Fly   240 VPRV-VCGEKHIIKGVSVHV 258
            ...: :.|.:  |.|.::||
plant   536 DEALQLSGSE--IGGGNIHV 553

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	13/70 (19%)
		RRM1_TDP43	108..181	CDD:409760	18/73 (25%)
		RRM2_TDP43	193..262	CDD:409761	20/85 (24%)
NUC-L2	NP_188491.1	RRM1_NUCLs	385..461	CDD:409884	18/76 (24%)
		RRM2_NUCLs	480..556	CDD:409885	20/76 (26%)