Protein Alignment cocoon and ncl

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001070120.3
• Gene: ncl / 767714
• ZFINID: ZDB-GENE-030131-6986
• Length: 704
• Species: Danio rerio
• Alignment Length: 337
• Identity: 77/337 - (22%)
• Similarity: 131/337 - (38%)
• Gaps: 68/337 - (20%)

  Fly     8 EKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGRLYSPSEETGWGEY 72
            |:|.|:..|..:||:.   :.|..|...:.:|:         |:....:|.......|:....|.
Zfish   201 EEEDDDEEEDDSEEEE---MDTTPAPKAKKAGM---------VKAKEESEEEDDDDEEDDDDEEE 253

  Fly    73 HYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAE 137
            ......|.  ||::|...|..|...|:.:.....|.|.:..|:.|....:|:.....:......|
Zfish   254 EETPATPA--KRKAETKKEKGTPPAKKAKTDGEGFSLFLGNLNNNKDFDELKSAISKFFSKEGLE 316

  Fly   138 IKKDTRSGHSKGFGFVRFGSYDVQMHVLSKRHSIDGRWC---EVKVPASRGMGNQEPGK------ 193
            | :|.|.|.:|.||:|.|.|.:    .|.|...::|:..   .||:..:|...|.:..|
Zfish   317 I-QDVRLGGTKKFGYVDFASEE----ELQKALELNGKKLLGQPVKLDKARSKENSQENKKERDAR 376

  Fly   194 -VFVGRCTEDIEADDLREYFSKFGEVIDVFIPK----PFRAFSFVTFLDPYVPRVVCGEKHI--- 250
             :||......|..|||||.|.   :.:|:.:|.    ..|..:::.|....:     .||.:
Zfish   377 TLFVKNLPYSITQDDLREIFD---QAVDIRVPMGNTGTSRGIAYIEFKTEAI-----AEKALEEA 433

  Fly   251 ----IKGVSVHVS-TADK-----KNVQNKNQLFQTNNY------NNLDNNFKMQPANNFRMHPAN 299
                ::|.|:.|. |.||     :...:.:::...||.      ::|.:.|  :.|.:.|: |.|
Zfish   434 QGSDVQGRSIIVDFTGDKSRQGGRGAPSASKVLVVNNLAFSASEDSLQSVF--EKAVSIRI-PQN 495

  Fly   300 NFSMHSFNPHGY 311
            |     ..|.||
Zfish   496 N-----GRPKGY 502

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	13/69 (19%)
		RRM1_TDP43	108..181	CDD:409760	20/75 (27%)
		RRM2_TDP43	193..262	CDD:409761	20/87 (23%)
ncl	NP_001070120.3	None