Protein Alignment cocoon and hnrnpd

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001025523.1
• Gene: hnrnpd / 594903
• XenbaseID: XB-GENE-988375
• Length: 295
• Species: Xenopus tropicalis
• Alignment Length: 267
• Identity: 72/267 - (26%)
• Similarity: 123/267 - (46%)
• Gaps: 49/267 - (18%)

  Fly    64 SEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFE 128
            :||||..|                 .::...:||:..|.     .:.:.|||::||::||::||.
 Frog    17 TEETGQNE-----------------GVKIDASKTEEDEG-----KMFIGGLSWDTTKKDLKDYFS 59

  Fly   129 TYGDVVKAEIKKDTRSGHSKGFGFVRF-GSYDVQMHVLSKRHSIDGRWCEVKVPASRGMGNQEP- 191
            .:|:||...:|.|..:|.|:|||||.| .|..|...:..|.|.::|:..:.|  .::.|..:||
 Frog    60 KFGEVVDCTLKLDPITGRSRGFGFVLFKESEGVDKVMEQKEHKLNGKVIDPK--RAKAMKTKEPV 122

  Fly   192 GKVFVGRCTEDIEADDLREYFSKFGEVIDVFIP-----KPFRAFSFVTFL--DPYVPRVVCGEKH 249
            .|:|||..:.|...:.:||||..|||:..:.:|     ...|.|.|:||.  || |.:::..:.|
 Frog   123 KKIFVGGLSPDTPEEKIREYFGTFGEIEAIELPMDNKTNKRRGFCFITFKEEDP-VKKIMEKKYH 186

  Fly   250 IIKGVSVHVSTADKKNVQNKNQLFQTNNYNNLDNNFKMQP----------ANNFRMHPANNFSMH 304
                 :|.:|..:.|...:|.|..|...:.........:|          :..:..:...::|.:
 Frog   187 -----NVGLSKCEIKVALSKEQYQQQQQWGTRGGGSSSRPRGRGGVSQTWSQGYSNYWNPSYSSY 246

  Fly   305 SFNPHGY 311
            .:|..||
 Frog   247 GYNNQGY 253

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	5/13 (38%)
		RRM1_TDP43	108..181	CDD:409760	28/73 (38%)
		RRM2_TDP43	193..262	CDD:409761	24/75 (32%)
hnrnpd	NP_001025523.1	RRM1_hnRNPD	40..113	CDD:410150	28/74 (38%)
		RRM2_hnRNPD	124..198	CDD:241027	25/79 (32%)