DRSC/TRiP Functional Genomics Resources

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Protein Alignment cocoon and dazap1

DIOPT Version :10

Sequence 1:NP_648764.1 Gene:cocoon / 39665 FlyBaseID:FBgn0036496 Length:318 Species:Drosophila melanogaster
Sequence 2:XP_021335308.1 Gene:dazap1 / 561459 ZFINID:ZDB-GENE-070212-1 Length:469 Species:Danio rerio


Alignment Length:228 Identity:71/228 - (31%)
Similarity:105/228 - (46%) Gaps:32/228 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 LIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVL-SKRHSID 172
            |.|.||.::||::.||.||..||:||...|.||..:..|:|||||:|...:....|| :|.|::|
Zfish    25 LFVGGLDWSTTQETLRNYFSQYGEVVDCVIMKDKSTNQSRGFGFVKFKDPNCVRTVLDTKPHNLD 89

  Fly   173 GRWCEVKVPASRGM----------------GNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDV 221
            ||..:.|....|||                .:.:..|:|||....:....:||:||::||.|.:|
Zfish    90 GRNIDPKPCTPRGMQPEKTRTKDGWKGSKSDSNKSKKIFVGGIPHNCGEAELRDYFNRFGVVTEV 154

  Fly   222 FI------PKPFRAFSFVTF-LDPYVPRVVCGEKHIIKGVSVHVSTADKKN--VQNKNQLFQTNN 277
            .:      .:| |.|.|:|| .:..|.:.|....|.|.|..|.|..|:.::  .....||    .
Zfish   155 VMIYDAEKQRP-RGFGFITFEAEQSVDQAVNMHFHDIMGKKVEVKKAEPRDSKAPAPGQL----G 214

  Fly   278 YNNLDNNFKMQPANNFRMHPANNFSMHSFNPHG 310
            .|.......:..||.:...||..: ..|:.|.|
Zfish   215 ANQWGPRAIISAANGWAAQPAPTW-QQSYGPQG 246

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cocoonNP_648764.1 TDP43_N 3..78 CDD:465833
RRM1_TDP43 108..181 CDD:409760 32/72 (44%)
RRM2_TDP43 193..262 CDD:409761 25/75 (33%)
dazap1XP_021335308.1 RRM1_DAZAP1 24..105 CDD:409988 35/79 (44%)
RRM2_DAZAP1 127..202 CDD:409765 25/75 (33%)
PRK10263 <220..>430 CDD:236669 7/28 (25%)
Blue background indicates that the domain is not in the aligned region.

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