Protein Alignment cocoon and hnrnpdl

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001011015.1
• Gene: hnrnpdl / 496424
• XenbaseID: XB-GENE-495016
• Length: 297
• Species: Xenopus tropicalis
• Alignment Length: 244
• Identity: 67/244 - (27%)
• Similarity: 111/244 - (45%)
• Gaps: 45/244 - (18%)

  Fly   109 LIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRF-GSYDVQMHVLSKRHSID 172
            :.:.|||::|:::||.||...:|:||...||.|..:|.|:|||||.| .:..|...:.:|.|.:|
 Frog    28 MFIGGLSWDTSKKDLTEYLSRFGEVVDCTIKTDPVTGRSRGFGFVLFKDAVSVDKVLETKEHKLD 92

  Fly   173 GRWCEVKVPASRGMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIP-----KPFRAFSF 232
            |:..:.| .|....|.:.|.|||||..:.:...:.:::||..|||:.::.:|     ...|.|.|
 Frog    93 GKLIDPK-RAKALKGKEPPKKVFVGGLSPETTEEQIKQYFGGFGEIENIELPMDTKTNERRGFCF 156

  Fly   233 VTFL--DPYVPRVVCGEKHIIKGVSVHVSTADKKNV----QNKNQL------------------- 272
            ||:.  :| |.:::....|.|......:..|..|.|    |.|.|.
 Frog   157 VTYTGEEP-VKKLLESRFHQIGTGKCEIKVAQPKEVYRQQQQKQQKGGRGAATGRGGARGRGRGQ 220

  Fly   273 --------FQTNNYNNLDNN--FKMQPANNFRMHPANNFSMHSFNPHGY 311
                    :...||.:..||  :..|..||  .:...::|.:::..:||
 Frog   221 GWNQGYSNYYDQNYGSYGNNGSYADQGYNN--SYSGYDYSGYNYGSYGY 267

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833
		RRM1_TDP43	108..181	CDD:409760	28/72 (39%)
		RRM2_TDP43	193..262	CDD:409761	20/75 (27%)
hnrnpdl	NP_001011015.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..21
		RRM1_hnRPDL	27..102	CDD:410152	28/74 (38%)
		RRM2_hnRPDL	112..186	CDD:409998	20/74 (27%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	192..224		3/31 (10%)
		Trnau1ap	223..>272	CDD:465438	10/47 (21%)