Protein Alignment cocoon and msi

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_733108.2
• Gene: msi / 43087
• FlyBaseID: FBgn0011666
• Length: 634
• Species: Drosophila melanogaster
• Alignment Length: 267
• Identity: 71/267 - (26%)
• Similarity: 110/267 - (41%)
• Gaps: 53/267 - (19%)

  Fly    12 DEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEGR-LYSPSEETGWGEYHYF 75
            ::|.:.||::....||.              .||:..|  |...|.|: ....|.::|
  Fly   142 EQPKQEPAQQAALALLK--------------ENVNASA--GAGQNNGQAAMGGSNKSG------- 183

  Fly    76 CVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYNTTEQDLREYFETYGDVVKAEIKK 140
                  :..:|..:|...:.......      .|.|.|||:.|:...|:|||..:|.|....|.|
  Fly   184 ------SSGRSTPSLSGGSGSDPAPG------KLFVGGLSWQTSSDKLKEYFNMFGTVTDVLIMK 236

  Fly   141 DTRSGHSKGFGFVRFGSYDVQMHVLS-KRHSIDGRWCEVK--VPASRGMGNQEPGKVFVGRCTED 202
            |..:..|:||||:.|........||. ..|::||:..:.|  .|.:|.....:..|:|||..::|
  Fly   237 DPVTQRSRGFGFITFQEPCTVEKVLKVPIHTLDGKKIDPKHATPKNRPRQANKTKKIFVGGVSQD 301

  Fly   203 IEADDLREYFSKFGEVIDVFI-----PKPFRAFSFVTFLDPYVPRVVCGEKHIIKGVSVHVSTAD 262
            ..|::::.|||:||.|.:..:     .|..|.|.||||.:..|...||         .:|..|..
  Fly   302 TSAEEVKAYFSQFGPVEETVMLMDQQTKRHRGFGFVTFENEDVVDRVC---------EIHFHTIK 357

  Fly   263 KKNVQNK 269
            .|.|:.|
  Fly   358 NKKVECK 364

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	13/66 (20%)
		RRM1_TDP43	108..181	CDD:409760	27/75 (36%)
		RRM2_TDP43	193..262	CDD:409761	24/73 (33%)
msi	NP_733108.2	RRM_SF	204..278	CDD:473069	27/73 (37%)
		RRM2_MSI	292..365	CDD:240769	27/82 (33%)