Protein Alignment cocoon and Hnrnpa3

DIOPT Version :10

• Sequence 1: NP_648764.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_937765.1
• Gene: Hnrnpa3 / 362152
• RGDID: 727807
• Length: 379
• Species: Rattus norvegicus
• Alignment Length: 258
• Identity: 74/258 - (28%)
• Similarity: 120/258 - (46%)
• Gaps: 48/258 - (18%)

  Fly    53 VRSNEGRLYSPSEETGWGEYHYFCVFPKKNKRQSEDNLENSTAKTKRTEAHLRCFDLIVLGLSYN 117
            |:...||   |..::|           ::.:|:.|:..:....:..|        .|.:.|||:.
  Rat     3 VKPPPGR---PQPDSG-----------RRRRRRGEEGHDPKEPEQLR--------KLFIGGLSFE 45

  Fly   118 TTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSY-DVQMHVLSKRHSIDGRWCEVKVP 181
            ||:..|||:||.:|.:....:.:|.::..|:|||||.:... :|...:.::.|.:|||..|.|..
  Rat    46 TTDDSLREHFEKWGTLTDCVVMRDPQTKRSRGFGFVTYSCVEEVDAAMCARPHKVDGRVVEPKRA 110

  Fly   182 ASRGMGNQEPG------KVFVGRCTEDIEADDLREYFSKFG--EVIDVFIPKPF---RAFSFVTF 235
            .|| ..:.:||      |:|||...||.|..:||:||.|:|  |.|:|...:..   |.|:||||
  Rat   111 VSR-EDSVKPGAHLTVKKIFVGGIKEDTEEYNLRDYFEKYGKIETIEVMEDRQSGKKRGFAFVTF 174

  Fly   236 LD-PYVPRVVCGEKHIIKGVSVHVSTA-DKKNVQNK-----------NQLFQTNNYNNLDNNF 285
            .| ..|.::|..:.|.|.|.:..|..| .|:.:|:.           |.:.:..|:.....||
  Rat   175 DDHDTVDKIVVQKYHTINGHNCEVKKALSKQEMQSAGSQRGRGGGSGNFMGRGGNFGGGGGNF 237

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_648764.1	TDP43_N	3..78	CDD:465833	5/24 (21%)
		RRM1_TDP43	108..181	CDD:409760	26/73 (36%)
		RRM2_TDP43	193..262	CDD:409761	30/75 (40%)
Hnrnpa3	NP_937765.1	Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	1..34		7/44 (16%)
		RRM1_hnRNPA_like	36..113	CDD:409992	26/76 (34%)
		RRM2_hnRNPA3	126..205	CDD:409996	30/78 (38%)
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	204..225		3/20 (15%)
		HnRNPA1	332..>348	CDD:463312
		Disordered. /evidence=ECO:0000256|SAM:MobiDB-lite	335..379