DRSC/TRiP Functional Genomics Resources

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Protein Alignment cocoon and hnrnpaba

DIOPT Version :10

Sequence 1:NP_648764.1 Gene:cocoon / 39665 FlyBaseID:FBgn0036496 Length:318 Species:Drosophila melanogaster
Sequence 2:NP_997752.2 Gene:hnrnpaba / 321466 ZFINID:ZDB-GENE-030131-185 Length:340 Species:Danio rerio


Alignment Length:213 Identity:60/213 - (28%)
Similarity:95/213 - (44%) Gaps:31/213 - (14%)


- Green bases have known domain annotations that are detailed below.


  Fly   109 LIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGS-YDVQMHVLSKRHSID 172
            :.|.|||::|:::||::||..:|:|....||.|..:|.|:||||:.|.. ..|...:..|.|.:|
Zfish    71 MFVGGLSWDTSKKDLKDYFSKFGEVTDCTIKMDPNTGRSRGFGFILFKEPSGVDKVLAQKEHRLD 135

  Fly   173 GRWCEVKVPASRGMGNQEPGKVFVGRCTEDIEADDLREYFSKFGEVIDVFIP-----KPFRAFSF 232
            ||..:.|  .:..|..:...|:|||....:...:.:||||..|||:..:.:|     ...|.|.|
Zfish   136 GRQIDPK--KAMAMKKEPVKKIFVGGLNPETTEERIREYFGAFGEIETIELPMDPKSNKRRGFVF 198

  Fly   233 VTFLDPYVPRVVCGEK-HIIKGVS--------VHVSTADKKNVQNKNQL--------------FQ 274
            :||.:....:.:..:| |.:.|..        ..:..|..|.|..:.|.              .|
Zfish   199 ITFKEEEAVKKILEKKYHNVSGTKDTSGKEGLCEIKIAQPKEVYQQQQYGGRFGGGGRGRGRGGQ 263

  Fly   275 TNNYNNLDNNFKMQPANN 292
            ..|:|...||:..|...|
Zfish   264 GQNWNQGYNNYWNQGYGN 281

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
cocoonNP_648764.1 TDP43_N 3..78 CDD:465833
RRM1_TDP43 108..181 CDD:409760 28/72 (39%)
RRM2_TDP43 193..262 CDD:409761 20/82 (24%)
hnrnpabaNP_997752.2 CBFNT 1..69 CDD:311868
RRM1_hnRNPAB 65..144 CDD:410151 28/74 (38%)
RRM2_hnRNPAB 149..228 CDD:409997 20/78 (26%)
Blue background indicates that the domain is not in the aligned region.

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