Protein Alignment cocoon and tdp-1

DIOPT Version :9

• Sequence 1: NP_001261874.1
• Gene: cocoon / 39665
• FlyBaseID: FBgn0036496
• Length: 318
• Species: Drosophila melanogaster
• Sequence 2: NP_001254189.1
• Gene: tdp-1 / 174436
• WormBaseID: WBGene00006514
• Length: 414
• Species: Caenorhabditis elegans
• Alignment Length: 306
• Identity: 108/306 - (35%)
• Similarity: 162/306 - (52%)
• Gaps: 42/306 - (13%)

  Fly     3 FVHVSEKEGDEPIELPAEEDGTLLLSTLQAQFPESSGLQYRNVDTKAVRGVRSNEG--RLYSPSE 65
            |:.|.:..||||||||. .||.:|::||||.||.::||:|:|..|.|.|.|:.:..  :|.:|::
 Worm    47 FITVQDPNGDEPIELPT-VDGVVLMTTLQASFPGATGLKYKNPKTGANRAVQVDPSGLKLIAPAD 110

  Fly    66 ETGWGEYHYFCVFPKKNKR-----------------------QSEDNLENSTAKTKRTEAHLRCF 107
              ||....:|.:...:::|                       .|:|..:..:.:.:..|...:..
 Worm   111 --GWENKTFFVIVAPQSERVRALSSADATSAKRRKVGSSDDSDSDDGRDGRSGRKRAVERDSQPV 173

  Fly   108 DLIVLGLSYNTTEQDLREYFETYGDVVKAEIKKDTRSGHSKGFGFVRFGSYDVQMHVLS-KRHSI 171
            ||||||:.:.||::..::|||..|.||..|||:.: .|:||||||||..|...|..||: .:|.|
 Worm   174 DLIVLGVDFKTTDECFQKYFEDIGTVVFCEIKRKS-DGNSKGFGFVRMSSVGEQNKVLAIPQHMI 237

  Fly   172 DGRWCEVKVPASRGM----GNQEPGKVFVGRCTEDIEADDLREYFS-------KFGEVIDVFIPK 225
            |||.|:||||..|.:    |.....::||||.|:.::...||:.|.       :...|.||||||
 Worm   238 DGRRCDVKVPDGRSLQDKQGRPSISRIFVGRLTDKVDEHQLRKVFGDEAKSYIETAVVTDVFIPK 302

  Fly   226 PFRAFSFVTFLD-PYVPRVVCGEKHIIKGVSVHVSTADKKNVQNKN 270
            |||.|:|||... ....|:|......:.|:||.:|.|..:...|::
 Worm   303 PFRGFAFVTLSSAEAAERIVSKGSLTVNGLSVGLSIAQPREENNQS 348

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
cocoon	NP_001261874.1	RRM1_TDP43	108..184	CDD:240767	40/76 (53%)
		RRM2_TDP43	193..262	CDD:240768	28/76 (37%)
tdp-1	NP_001254189.1	RRM_SF	174..247	CDD:302621	38/73 (52%)
		RRM_SF	262..339	CDD:302621	28/76 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C160167671
Domainoid	1	1.000	64	1.000	Domainoid score	I6685
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	1	1.000	-	-		H134087
Inparanoid	1	1.050	183	1.000	Inparanoid score	I2627
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG48344
OrthoDB	1	1.010	-	-		D390211at33208
OrthoFinder	1	1.000	-	-		FOG0005498
OrthoInspector	1	1.000	-	-		otm14766
orthoMCL	1	0.900	-	-		OOG6_105367
Panther	1	1.100	-	-	O	PTHR48033
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X3916
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	14	13.910