back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Toll-6 and PSY1R

DIOPT Version :9

Sequence 1:	NP_001246765.1	Gene:	Toll-6 / 39663	FlyBaseID:	FBgn0036494	Length:	1514	Species:	Drosophila melanogaster
Sequence 2:	NP_177374.1	Gene:	PSY1R / 843562	AraportID:	AT1G72300	Length:	1095	Species:	Arabidopsis thaliana

Alignment Length:	1074	Identity:	220/1074 - (20%)
Similarity:	371/1074 - (34%)	Gaps:	335/1074 - (31%)

- Green bases have known domain annotations that are detailed below.

  Fly   200 RRLERLDLSSNNI-WSLPDNIFCTLSELSALNMSENRLQDVNELGFRDRSKEPTNGSTE------ 257
            :||.|||||.|.: ..||......|.:|..|::|.|..:  .||..:......:||...
plant   116 QRLSRLDLSHNRLSGPLPPGFLSALDQLLVLDLSYNSFK--GELPLQQSFGNGSNGIFPIQTVDL 178

  Fly   258 STSTTESAKKSSSSSTSCSLDLEYLDVSHNDFV-VLPANGFGTLRRLRVLSVNNNGISMIADKAL 321
            |::..|....|||.....:.:|...:||:|.|. .:|:.......:|..|..:.|..|....:.|
plant   179 SSNLLEGEILSSSVFLQGAFNLTSFNVSNNSFTGSIPSFMCTASPQLTKLDFSYNDFSGDLSQEL 243

  Fly   322 SGLKNLQILNLSSNKIVALPTELFAEQAKIIQEVYLQNNSISVLNPQLFSNLDQLQALDLSMNQI 386
            |....|.:|....|.:          ..:|.:|:|               ||.:|:.|.|.:|::
plant   244 SRCSRLSVLRAGFNNL----------SGEIPKEIY---------------NLPELEQLFLPVNRL 283

  Fly   387 TSTWIDKNTFVGLIRLVLLNLSHNKLTKLEPEIFSDLYTLQILNLRHNQLENIAADTFAPMNNLH 451
            :.. || |....|.:|.||.|..|.:....|:....|..|..|.|..|.|......:.|....|.
plant   284 SGK-ID-NGITRLTKLTLLELYSNHIEGEIPKDIGKLSKLSSLQLHVNNLMGSIPVSLANCTKLV 346

  Fly   452 TLLLSHNKL-KYLDAYALNGLYVLSLLSLDNNALIGVHPDAFRNCSALQDLNLNGNQL--KTVPL 513
            .|.|..|:| ..|.|...:....||:|.|.||:..|..|....:|..:..:...||:|  :..|.
plant   347 KLNLRVNQLGGTLSAIDFSRFQSLSILDLGNNSFTGEFPSTVYSCKMMTAMRFAGNKLTGQISPQ 411

  Fly   514 ALRNMRHLRTVDLGENMITVMED--SAFKGLGNLYGLRLIGNYLENITMHTFRD------LPNLQ 570
            .| .:..|......:|.:|.:..  |..:|...|..|.:..|:.:. |:.:.:|      .|:||
plant   412 VL-ELESLSFFTFSDNKMTNLTGALSILQGCKKLSTLIMAKNFYDE-TVPSNKDFLRSDGFPSLQ 474

  Fly   571 ILNLARNRIAVVEPGAFEMTSSIQA--VRLDGNELNDIN---------GLFSNMPSLLWLNISDN 624
            |..:          ||..:|..|.|  ::|...|:.|::         |....:|.|.:|::|||
plant   475 IFGI----------GACRLTGEIPAWLIKLQRVEVMDLSMNRFVGTIPGWLGTLPDLFYLDLSDN 529

  Fly   625 RLESFDYGHVPSTL-QWLDLHKNRLSSLSNRFGLDSELKLQ----TLDVSFNQLQRIGPS----- 679
                |..|.:|..| |...|...:....:.|..|:..:.:.    |.:..:|||..:.|:
plant   530 ----FLTGELPKELFQLRALMSQKAYDATERNYLELPVFVNPNNVTTNQQYNQLSSLPPTIYIKR 590

  Fly   680 -----SIPNSIELL-------FLNDNLITTVDPDTFMHKTNLTRVDLYANQIT---TLDIKSLRI 729
                 :||..:..|       .|.:|...:: ||...:.|||.|:||..|.::   ...:..|..
plant   591 NNLTGTIPVEVGQLKVLHILELLGNNFSGSI-PDELSNLTNLERLDLSNNNLSGRIPWSLTGLHF 654

  Fly   730 LPVW---------------EHRALPEFYIGGNPFTC------DCNIDWLQKINHITSR----QYP 769
            |..:               :....|:....|||..|      .|:     ...|.|::    :..
plant   655 LSYFNVANNTLSGPIPTGTQFDTFPKANFEGNPLLCGGVLLTSCD-----PTQHSTTKMGKGKVN 714

  Fly   770 RIM------------DLETIYCKLLNNRERAYIPLIEAEPKHFLCTYKTHCFAVCHCCEFDACDC 822
            |.:            .|..:...||...:|...|                         .|:.:.
plant   715 RTLVLGLVLGLFFGVSLILVLLALLVLSKRRVNP-------------------------GDSENA 754

  Fly   823 EMTCPTNCTCFHDQTWSTNIVECSGAAYSEMPRRVPMDTSELYIDGNNFVELAGHSFLGRKNLAV 887
            |:...:|                  .:|||:|.....|.|.:.:.||:..|:        |:|.:
plant   755 ELEINSN------------------GSYSEVPPGSDKDISLVLLFGNSRYEV--------KDLTI 793

  Fly   888 LYANNSNVAHIYNTTFSGLKRLLILHLEDNHIISLEGNEFHNLENLRELYLQSNKI--------- 943
            ..                     :|...||                   :.|:|.|
plant   794 FE---------------------LLKATDN-------------------FSQANIIGCGGFGLVY 818

  Fly   944 -ASIANGSFQMLRKLEVLRLDGNRLMHFEVWQLSANPYLVEISLADNQWSCECGYLARFRNYLGQ 1007
             |::.||:     ||.|.:|.|                  :..:.:.::..|...|:|.::
plant   819 KATLDNGT-----KLAVKKLTG------------------DYGMMEKEFKAEVEVLSRAKH---- 856

  Fly  1008 SSEKIIDASRVSCIYNNATSVLRE--KNGTKCTLRDGVAHYMHTNEIEGLLPL-------LLVAT 1063
              |.:: |.:..|::::|..::..  :||:       :.:::|.|. ||...|       ::...
plant   857 --ENLV-ALQGYCVHDSARILIYSFMENGS-------LDYWLHENP-EGPAQLDWPKRLNIMRGA 910

  Fly  1064 CAFVAFFGLIFGLFCYRHELKIWAHSTNCLMNFCYKSPRFVDQLDKERPNDAYFAYSLQDEHFVN 1128
            .:.:|:...|    |..|.:.....|:|.|::..:|               ||.|
plant   911 SSGLAYMHQI----CEPHIVHRDIKSSNILLDGNFK---------------AYVA---------- 946

  Fly  1129 QILAQTLENDIGY-RLCLHYRDVNINAYITDALI 1161
                     |.|. ||.|.||     .::|..|:
plant   947 ---------DFGLSRLILPYR-----THVTTELV 966

Known Domains:

Indicated by green bases in alignment.

Software error:

Illegal division by zero at /www/www.flyrnai.org/docroot/cgi-bin/DRSC_prot_align.pl line 591.

For help, please send mail to the webmaster (ritg@hms.harvard.edu), giving this error message and the time and date of the error.