DRSC/TRiP Functional Genomics Resources

powered by:
logo

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits


Protein Alignment Toll-6 and RLP40

DIOPT Version :9

Sequence 1:NP_001246765.1 Gene:Toll-6 / 39663 FlyBaseID:FBgn0036494 Length:1514 Species:Drosophila melanogaster
Sequence 2:NP_566757.2 Gene:RLP40 / 822091 AraportID:AT3G24982 Length:915 Species:Arabidopsis thaliana


Alignment Length:940 Identity:203/940 - (21%)
Similarity:329/940 - (35%) Gaps:281/940 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   196 FSVTRRLERLDLS-------SNNIWSL------------PDNIF-----------CTLSELSALN 230
            ||:|..:.:..||       |..::||            |.:.|           |...::.|..
plant    13 FSLTFLISKSILSFKAVFIMSELLFSLNFLLLLLLSCVSPSSFFTFNNPVVGLGACGPHQIQAFT 77

  Fly   231 MSENRLQDVNELGFRDRS---KEPTNG-----STESTSTTE-SAKKSSSSSTSCSL----DLEYL 282
            ..:|.        |..|:   .:|.||     ||.:.:..: .|..|.:...:.||    .|..|
plant    78 QFKNE--------FDTRACNHSDPWNGVWCDDSTGAVTMLQLRACLSGTLKPNSSLFQFHHLRSL 134

  Fly   283 DVSHNDFVVLP-ANGFGTLRRLRVLSVNNNGISMIADKALSGLKNLQILNLSSNKIVALPTELFA 346
            .:.||:|.... ::.||.|..|.|||::::|.......:.|.|..|..|.||:|.:         
plant   135 LLPHNNFTSSSISSKFGMLNNLEVLSLSSSGFLAQVPFSFSNLSMLSALVLSNNDL--------- 190

  Fly   347 EQAKIIQEVYLQNNSISVLNPQLFSNLDQLQALDLSMNQITSTWIDKNTFVGLIRLVLLNLSHNK 411
                        ..|:|...     ||.:|:.||:|.|..:......::...|..::.|||.:|.
plant   191 ------------TGSLSFAR-----NLRKLRVLDVSYNHFSGILNPNSSLFELHHIIYLNLRYNN 238

  Fly   412 LTKLE-PEIFSDLYTLQILNLRHNQLENIAADTFAPMNNLHTLLLSHNKLKYLDAYAL-NGLYVL 474
            .|... |..|.:|..|::|::..|........|.:.:..|..|.|..|  .:..:..| ..|..|
plant   239 FTSSSLPYEFGNLNKLEVLDVSSNSFFGQVPPTISNLTQLTELYLPLN--HFTGSLPLVQNLTKL 301

  Fly   475 SLLSLDNNALIGVHPDAFRNCSALQDLNLNGNQLK---TVPLALRNMRHLRTVDLGEN------- 529
            |:|.|..|...|..|.:......|..|:|.||.|.   .||.:..:.| |.::.||||       
plant   302 SILHLFGNHFSGTIPSSLFTMPFLSYLSLKGNNLNGSIEVPNSSSSSR-LESLHLGENHFEGKIL 365

  Fly   530 -----MITVME------------D-SAFKGLGNLYGLRLIGNYLENITMHTFRDLPN-LQILNLA 575
                 :|.:.|            | |.|..|.:|..|.|.|:::...::.....:|: |::|.|.
plant   366 EPISKLINLKELDLSFLNTSYPIDLSLFSSLKSLLLLDLSGDWISKASLTLDSYIPSTLEVLRLE 430

  Fly   576 RNRIAVVEPGAFEMTSSIQAVRLDGNELNDINGLFSNMPSLLW-------LNISDNRLESFDYGH 633
            ...|:.. |..|:...:::.:.|..|.   |:|.|   |..||       :.|:||.|..|:...
plant   431 HCDISDF-PNVFKTLHNLEYIALSNNR---ISGKF---PEWLWSLPRLSSVFITDNLLTGFEGSS 488

  Fly   634 ---VPSTLQWLDLHKNRL--------------SSLSNRFGLDSEL------KLQTLDVSFNQLQR 675
               |.|::|.|.|..|.|              |::.||||.|..|      .|..||:|:|....
plant   489 EVLVNSSVQILSLDTNSLEGALPHLPLSINYFSAIDNRFGGDIPLSICNRSSLDVLDLSYNNFTG 553

  Fly   676 IGPSSIPNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYANQIT------TLDIKSLRILPVWE 734
            ..|..:.|.:.|....:||..:: ||.:...|.|..:|:..|::|      .::..:|:.|.| :
plant   554 PIPPCLSNLLYLKLRKNNLEGSI-PDKYYEDTPLRSLDVGYNRLTGKLPRSLINCSALQFLSV-D 616

  Fly   735 HRALPEFYIGGNPFTCDCNIDWLQKINHITSRQYPRIMDLETIYCKLLNNRERAYIPLIEAEPKH 799
            |..:.:.:    ||:.               :..|::.       .||.:..:.|.||       
plant   617 HNGIKDTF----PFSL---------------KALPKLQ-------VLLLSSNKFYGPL------- 648

  Fly   800 FLCTYKTHCFAVCHCCEFDACDCEMTCPTNCTCFHDQTWSTNIVECSGAAYSEMPRRVPMDTSEL 864
                                                                ..|...|:...||
plant   649 ----------------------------------------------------SPPNEGPLGFPEL 661

  Fly   865 YIDGNNFVELAGHSFLGRKNLAVLYANNSNVAH----------IYNTTFSGLKRLLI-------- 911
            .|     :|:||:...|....:..:.|....:|          :|.....|...|..        
plant   662 RI-----LEIAGNKLTGSFLSSDFFVNWKASSHTMNEDLGLYMVYGKVIFGNYHLTYYETIDLRY 721

  Fly   912 --LHLEDNHI------ISLEGNEFHN--------LENLRELYLQSNKIASIANGSFQMLRKLEVL 960
              |.:|..::      |...||....        |:.|..|.|.:|........||..|:|:|.|
plant   722 KGLSMEQRNVLTSSATIDFSGNRLEGEIPESIGLLKALIALNLSNNAFTGHIPLSFANLKKMESL 786

  Fly   961 RLDGNRLMHFEVWQLSANPYLVEISLADNQ 990
            .|..|:|.......|....:|..::::.||
plant   787 DLSSNQLSGTIPNGLRTLSFLAYVNVSHNQ 816

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-6NP_001246765.1 leucine-rich repeat 148..171 CDD:275380
LRR_8 171..236 CDD:290566 13/69 (19%)
leucine-rich repeat 172..201 CDD:275380 3/4 (75%)
leucine-rich repeat 202..278 CDD:275380 21/118 (18%)
leucine-rich repeat 229..249 CDD:275380 3/22 (14%)
LRR_RI 278..468 CDD:238064 46/191 (24%)
leucine-rich repeat 279..302 CDD:275380 8/23 (35%)
LRR_8 301..386 CDD:290566 21/84 (25%)
leucine-rich repeat 303..326 CDD:275380 7/22 (32%)
leucine-rich repeat 327..350 CDD:275380 5/22 (23%)
LRR 350..729 CDD:227223 111/445 (25%)
leucine-rich repeat 352..375 CDD:275380 4/22 (18%)
leucine-rich repeat 376..401 CDD:275380 6/24 (25%)
LRR_RI <401..626 CDD:238064 67/262 (26%)
leucine-rich repeat 402..425 CDD:275380 8/23 (35%)
leucine-rich repeat 426..449 CDD:275380 4/22 (18%)
leucine-rich repeat 450..473 CDD:275380 6/23 (26%)
leucine-rich repeat 474..497 CDD:275380 7/22 (32%)
leucine-rich repeat 498..518 CDD:275380 8/22 (36%)
leucine-rich repeat 521..544 CDD:275380 11/47 (23%)
leucine-rich repeat 545..566 CDD:275380 4/20 (20%)
leucine-rich repeat 569..592 CDD:275380 6/22 (27%)
leucine-rich repeat 593..615 CDD:275380 5/21 (24%)
leucine-rich repeat 616..637 CDD:275380 8/30 (27%)
leucine-rich repeat 638..662 CDD:275380 12/43 (28%)
leucine-rich repeat 663..684 CDD:275380 6/20 (30%)
leucine-rich repeat 685..708 CDD:275380 5/22 (23%)
leucine-rich repeat 709..728 CDD:275380 4/24 (17%)
LRR_8 883..943 CDD:290566 15/93 (16%)
leucine-rich repeat 885..908 CDD:275380 4/32 (13%)
leucine-rich repeat 909..932 CDD:275380 7/46 (15%)
LRR_8 932..990 CDD:290566 15/57 (26%)
leucine-rich repeat 933..956 CDD:275380 7/22 (32%)
TIR 1114..1247 CDD:214587
RLP40NP_566757.2 LRR_RI 97..>263 CDD:238064 46/191 (24%)
LRR_8 130..190 CDD:290566 20/59 (34%)
leucine-rich repeat 131..155 CDD:275380 8/23 (35%)
leucine-rich repeat 156..179 CDD:275380 7/22 (32%)
leucine-rich repeat 180..202 CDD:275380 9/47 (19%)
LRR_8 201..264 CDD:290566 17/62 (27%)
leucine-rich repeat 203..228 CDD:275380 6/24 (25%)
leucine-rich repeat 229..253 CDD:275380 8/23 (35%)
leucine-rich repeat 254..277 CDD:275380 4/22 (18%)
leucine-rich repeat 278..300 CDD:275380 6/23 (26%)
leucine-rich repeat 301..324 CDD:275380 7/22 (32%)
leucine-rich repeat 325..349 CDD:275380 8/23 (35%)
leucine-rich repeat 350..371 CDD:275380 5/20 (25%)
LRR_8 422..481 CDD:290566 17/65 (26%)
leucine-rich repeat 424..446 CDD:275380 6/22 (27%)
leucine-rich repeat 447..468 CDD:275380 8/26 (31%)
leucine-rich repeat 471..495 CDD:275380 6/23 (26%)
leucine-rich repeat 517..540 CDD:275380 7/22 (32%)
leucine-rich repeat 541..585 CDD:275380 12/44 (27%)
LRR_8 560..620 CDD:290566 15/61 (25%)
leucine-rich repeat 563..583 CDD:275380 5/20 (25%)
leucine-rich repeat 586..609 CDD:275380 4/22 (18%)
leucine-rich repeat 610..633 CDD:275380 6/42 (14%)
leucine-rich repeat 634..660 CDD:275380 7/91 (8%)
leucine-rich repeat 735..758 CDD:275380 4/22 (18%)
leucine-rich repeat 759..782 CDD:275380 7/22 (32%)
LRR_8 762..817 CDD:290566 16/55 (29%)
leucine-rich repeat 783..806 CDD:275380 6/22 (27%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 00.000 Not matched by this tool.
Phylome 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
00.000

Return to query results.
Submit another query.