DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-6 and vasna

DIOPT Version :9

Sequence 1:NP_001246765.1 Gene:Toll-6 / 39663 FlyBaseID:FBgn0036494 Length:1514 Species:Drosophila melanogaster
Sequence 2:NP_001313614.1 Gene:vasna / 553185 ZFINID:ZDB-GENE-050522-43 Length:688 Species:Danio rerio


Alignment Length:481 Identity:110/481 - (22%)
Similarity:176/481 - (36%) Gaps:155/481 - (32%)


- Green bases have known domain annotations that are detailed below.


  Fly   405 LNLSHNKLTKLEPEIFSDLYTLQILNLRHNQLENIAADTFAPMNNLHTLLLSHNKLKYLDAYALN 469
            |.:..||:..|:.:.|.:|..|::|:|..|.|..|....|:|:::||.|.||.|.:.::...:..
Zfish    57 LYVFQNKINILQQQDFVELGELEMLDLSQNSLSEIPDGVFSPLSSLHNLDLSSNYITHISKDSFI 121

  Fly   470 GLYVLSLLSLDNNALIGVHPDAFRNCSALQDLNLNGNQLKTVP-LALRNMRHLRTVDLGENMI-- 531
            ||..|..|.|.:|.:..:||.||.....|.:|.|.|||:..:| |.|..:.||   ||..|.|  
Zfish   122 GLVNLERLYLYSNIIQNIHPAAFEGLENLLELKLQGNQISVLPALQLPRLLHL---DLSYNSIPP 183

  Fly   532 TVMEDSAFKGLGNLYGLRLIGNYLENITMHTFRDLPNLQILNLARNRIAVVEPGAFEMTSSIQAV 596
            .|.:|..   ..:|..|::.|..|.::.......|.||.:|::::|::..::| ..:....::.:
Zfish   184 LVAQDLQ---TPHLESLKIAGLGLTSLDEELLGSLVNLHVLDVSQNQLVDIQP-TLKSMGGLRNL 244

  Fly   597 RLDGNELNDI-NGLFSNMPSLLWLNISDNRLESFDYGHVPSTLQWLDLHKNRLSSLSNRFGLDSE 660
            .|.||.|..: :..|.|:.:||.|::|:..|:.|..|.                     |.|   
Zfish   245 NLTGNPLGSLKHEDFQNLVNLLELDLSNLNLQGFPEGF---------------------FNL--- 285

  Fly   661 LKLQTLDVSFNQLQRIGPSSIPNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYANQITTLDIK 725
                     |.:|::                                 ||..:            
Zfish   286 ---------FPKLEK---------------------------------LTAAE------------ 296

  Fly   726 SLRILPVWEHRALPEFYIGGNPFTCDCNIDWLQKINHITSRQYPRIMDLETIYCKLLNNRE-RAY 789
                                |||.|.|.:.|           :|..  |:.:..:||...| |.:
Zfish   297 --------------------NPFNCLCPLAW-----------FPAW--LKDVRVELLRTEETRCH 328

  Fly   790 IPLIEA-------EPKHFLCTYKTHCFAVCHCCEFDACDCEMTC--PTNCTCFHDQTWSTNIVEC 845
            .|.|.:       |.|.|.|...|        .|..:.....|.  |.|.:   .|..:|:||  
Zfish   329 FPPINSGKVLEKLEHKDFGCPTTT--------IELTSAGTSSTTSKPKNSS---TQLGTTHIV-- 380

  Fly   846 SGAAYSEMPRRVPMDTSELYIDGNNF 871
                    |...|.|.|.  .|.:||
Zfish   381 --------PPAPPSDISS--ADADNF 396

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-6NP_001246765.1 leucine-rich repeat 148..171 CDD:275380
LRR_8 171..236 CDD:290566
leucine-rich repeat 172..201 CDD:275380
leucine-rich repeat 202..278 CDD:275380
leucine-rich repeat 229..249 CDD:275380
LRR_RI 278..468 CDD:238064 20/62 (32%)
leucine-rich repeat 279..302 CDD:275380
LRR_8 301..386 CDD:290566
leucine-rich repeat 303..326 CDD:275380
leucine-rich repeat 327..350 CDD:275380
LRR 350..729 CDD:227223 76/327 (23%)
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
LRR_RI <401..626 CDD:238064 67/224 (30%)
leucine-rich repeat 402..425 CDD:275380 6/19 (32%)
leucine-rich repeat 426..449 CDD:275380 8/22 (36%)
leucine-rich repeat 450..473 CDD:275380 8/22 (36%)
leucine-rich repeat 474..497 CDD:275380 8/22 (36%)
leucine-rich repeat 498..518 CDD:275380 9/20 (45%)
leucine-rich repeat 521..544 CDD:275380 7/24 (29%)
leucine-rich repeat 545..566 CDD:275380 4/20 (20%)
leucine-rich repeat 569..592 CDD:275380 4/22 (18%)
leucine-rich repeat 593..615 CDD:275380 6/22 (27%)
leucine-rich repeat 616..637 CDD:275380 7/20 (35%)
leucine-rich repeat 638..662 CDD:275380 2/23 (9%)
leucine-rich repeat 663..684 CDD:275380 2/20 (10%)
leucine-rich repeat 685..708 CDD:275380 0/22 (0%)
leucine-rich repeat 709..728 CDD:275380 2/18 (11%)
LRR_8 883..943 CDD:290566
leucine-rich repeat 885..908 CDD:275380
leucine-rich repeat 909..932 CDD:275380
LRR_8 932..990 CDD:290566
leucine-rich repeat 933..956 CDD:275380
TIR 1114..1247 CDD:214587
vasnaNP_001313614.1 None
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45836
Phylome 1 0.910 - -
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 1 1.000 - -
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
33.010

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