Protein Alignment Toll-6 and Lrrc17

DIOPT Version :10

• Sequence 1: NP_524081.1
• Gene: Toll-6 / 39663
• FlyBaseID: FBgn0036494
• Length: 1514
• Species: Drosophila melanogaster
• Sequence 2: NP_001020326.1
• Gene: Lrrc17 / 502715
• RGDID: 1560165
• Length: 446
• Species: Rattus norvegicus
• Alignment Length: 337
• Identity: 89/337 - (26%)
• Similarity: 140/337 - (41%)
• Gaps: 79/337 - (23%)

  Fly   330 LNLSSNKIV-ALPTELFAEQAKIIQEVYLQNNSISVLNPQLFSNLDQLQALDLSMNQITSTWIDK 393
            |:....|:| .||     :..:.:..:.|..|.|.||...:||...:|::|||..|:|:.  |:.
  Rat    70 LDCQERKLVYVLP-----DWPQDLLHMLLARNKIRVLKNNMFSKFKRLKSLDLQQNEISK--IES 127

  Fly   394 NTFVGLIRLVLLNLSHNKLTKLEPEIFSDLYT--LQILNLRHN------QLENIAADTFAPMNNL 450
            ..|.||.:|..|.|.||::..|..|:|  :||  |..|.|..|      :||.:.:....|.|
  Rat   128 EAFFGLNKLTTLLLQHNQIKVLTEEVF--IYTPLLSYLRLYDNPWHCACELETLVSMLQIPRN-- 188

  Fly   451 HTLLLSHNKLKYLDAYALNGLYVLSLLSLDNNALIGVHPDAFRNCSALQDLNLNG-NQLKTVPLA 514
                      :.|..||..|    |..:|.|..|:.:.|...  |...:...|:. .|:..||..
  Rat   189 ----------RNLGNYAKCG----SPPALRNKKLLQLKPQEL--CDEEEKERLDPIPQVSGVPAV 237

  Fly   515 LR-----NMRH-----LRTVDLGENMITVMEDSAFKGLGNLYGLRLIGNYLENITMHTFRDLPNL 569
            :|     .:.|     ::|:|....                 .|:.:.|   ||.       ||:
  Rat   238 IRPEADSTLCHNYVFPIQTLDCKRK-----------------ELKKVPN---NIP-------PNI 275

  Fly   570 QILNLARNRIAVVEPGAFEMTSSIQAVRLDGNELNDIN-GLFSNMPSLLWLNISDNRLESFDYGH 633
            ..|:|:.|:|:.:.|..||....::.:.|..|.|..|: ..|..:..|..|::|:|.|:|||||.
  Rat   276 VKLDLSYNKISQLRPKEFEDVHELKKLNLSSNGLEFIDPAAFLGLIHLEELDLSNNSLQSFDYGV 340

  Fly   634 VPS----TLQWL 641
            :..    .|.||
  Rat   341 LEDLYFLKLLWL 352

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-6	NP_524081.1	PPP1R42	<135..>242	CDD:455733
		leucine-rich repeat	148..171	CDD:275380
		leucine-rich repeat	172..201	CDD:275380
		LRR_8	200..>246	CDD:404697
		leucine-rich repeat	202..278	CDD:275380
		leucine-rich repeat	229..249	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR	299..654	CDD:443914	89/337 (26%)
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380	5/20 (25%)
		leucine-rich repeat	352..375	CDD:275380	7/22 (32%)
		leucine-rich repeat	376..401	CDD:275380	10/24 (42%)
		leucine-rich repeat	402..425	CDD:275380	8/22 (36%)
		leucine-rich repeat	426..449	CDD:275380	7/28 (25%)
		leucine-rich repeat	450..473	CDD:275380	4/22 (18%)
		leucine-rich repeat	474..497	CDD:275380	6/22 (27%)
		leucine-rich repeat	498..518	CDD:275380	5/25 (20%)
		leucine-rich repeat	521..544	CDD:275380	2/22 (9%)
		leucine-rich repeat	545..566	CDD:275380	4/20 (20%)
		leucine-rich repeat	569..592	CDD:275380	7/22 (32%)
		leucine-rich repeat	593..615	CDD:275380	5/22 (23%)
		leucine-rich repeat	616..637	CDD:275380	10/24 (42%)
		leucine-rich repeat	638..662	CDD:275380	3/4 (75%)
		LRR_8	662..719	CDD:404697
		leucine-rich repeat	663..684	CDD:275380
		leucine-rich repeat	685..708	CDD:275380
		leucine-rich repeat	709..728	CDD:275380
		LRR	<863..>990	CDD:443914
		leucine-rich repeat	885..908	CDD:275380
		leucine-rich repeat	909..932	CDD:275380
		leucine-rich repeat	933..956	CDD:275380
		TIR	1114..1247	CDD:214587
Lrrc17	NP_001020326.1	leucine-rich repeat	68..86	CDD:275380	5/20 (25%)
		LRR	<89..>356	CDD:443914	84/313 (27%)
		leucine-rich repeat	89..111	CDD:275380	7/21 (33%)
		leucine-rich repeat	112..135	CDD:275380	10/24 (42%)
		leucine-rich repeat	136..159	CDD:275380	10/24 (42%)
		PCC	141..>247	CDD:188093	31/125 (25%)
		leucine-rich repeat	160..210	CDD:275380	16/65 (25%)
		leucine-rich repeat	211..274	CDD:275380	14/91 (15%)
		leucine-rich repeat	275..298	CDD:275380	7/22 (32%)
		leucine-rich repeat	299..322	CDD:275380	5/22 (23%)
		leucine-rich repeat	323..346	CDD:275380	10/22 (45%)