DRSC/TRiP Functional Genomics Resources

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Protein Alignment Toll-6 and lrrc17

DIOPT Version :9

Sequence 1:NP_001246765.1 Gene:Toll-6 / 39663 FlyBaseID:FBgn0036494 Length:1514 Species:Drosophila melanogaster
Sequence 2:XP_009298620.1 Gene:lrrc17 / 321202 ZFINID:ZDB-GENE-030131-9774 Length:435 Species:Danio rerio


Alignment Length:345 Identity:73/345 - (21%)
Similarity:121/345 - (35%) Gaps:101/345 - (29%)


- Green bases have known domain annotations that are detailed below.


  Fly   682 PNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYANQITTLD------IKSLRILPVWEHR---- 736
            |..|..|.|..|.|..:..:||.|..||..:||..|:|:.:|      :..|..|.:..:|    
Zfish    68 PEDIHHLLLARNRIQVLRDNTFSHFRNLKSLDLQQNEISRIDDGAFDGLSKLTTLLLQHNRLQVA 132

  Fly   737 ------ALPE---FYIGGNPFTCDCNIDWLQKINHITSRQ----YPRIMD--------LETIYCK 780
                  .:|:   ..:..||:.|||.:|.|.:...:.|.:    |.|..:        |:.:..:
Zfish   133 SEGMLIPMPQLKYLRLHDNPWRCDCQLDSLVRFIQVPSNRNIGNYARCAEPREFSGRQLKKLDAE 197

  Fly   781 LLNNRERAYIPLIEAEPKHFLCTY-KTHCFAVCHCCEFDACDCEMTCPTNCTCFHDQTWSTNIVE 844
            :|.:.|:....:::.|.:...... |:...::||                 |..|    ....::
Zfish   198 MLCSPEQEKEAILDPENQQLPAPQKKSDATSLCH-----------------TYMH----PVPRMD 241

  Fly   845 CSGAAYSEMPRRVPMDTSELYIDGNNFVELAGHSFLGRKNLAVLYANNSNVAHIYNTTFSGLKRL 909
            |.......:|..:|:|                                                :
Zfish   242 CRNRDLKTVPADIPLD------------------------------------------------I 258

  Fly   910 LILHLEDNHIISLEGNEFHNLENLRELYLQSNKIASIANGSFQMLRKLEVLRLDGNRLMHFEVWQ 974
            :.|.|..|.|..|...||.|::.|:.|.|..|.:.||...:|..|..|..|.|..|.|.:|:...
Zfish   259 VKLDLSRNTIKQLRQKEFVNVKELKLLNLSGNSLESIDTAAFTGLLYLGELDLSNNSLRYFQYGV 323

  Fly   975 LSANPYLVEISLADNQWSCE 994
            |....:|..:||.||.|.|:
Zfish   324 LEDLYFLKRLSLGDNPWICD 343

Known Domains:


Indicated by green bases in alignment.

GeneSequenceDomainRegion External IDIdentity
Toll-6NP_001246765.1 leucine-rich repeat 148..171 CDD:275380
LRR_8 171..236 CDD:290566
leucine-rich repeat 172..201 CDD:275380
leucine-rich repeat 202..278 CDD:275380
leucine-rich repeat 229..249 CDD:275380
LRR_RI 278..468 CDD:238064
leucine-rich repeat 279..302 CDD:275380
LRR_8 301..386 CDD:290566
leucine-rich repeat 303..326 CDD:275380
leucine-rich repeat 327..350 CDD:275380
LRR 350..729 CDD:227223 17/52 (33%)
leucine-rich repeat 352..375 CDD:275380
leucine-rich repeat 376..401 CDD:275380
LRR_RI <401..626 CDD:238064
leucine-rich repeat 402..425 CDD:275380
leucine-rich repeat 426..449 CDD:275380
leucine-rich repeat 450..473 CDD:275380
leucine-rich repeat 474..497 CDD:275380
leucine-rich repeat 498..518 CDD:275380
leucine-rich repeat 521..544 CDD:275380
leucine-rich repeat 545..566 CDD:275380
leucine-rich repeat 569..592 CDD:275380
leucine-rich repeat 593..615 CDD:275380
leucine-rich repeat 616..637 CDD:275380
leucine-rich repeat 638..662 CDD:275380
leucine-rich repeat 663..684 CDD:275380 1/1 (100%)
leucine-rich repeat 685..708 CDD:275380 8/22 (36%)
leucine-rich repeat 709..728 CDD:275380 6/24 (25%)
LRR_8 883..943 CDD:290566 12/59 (20%)
leucine-rich repeat 885..908 CDD:275380 0/22 (0%)
leucine-rich repeat 909..932 CDD:275380 8/22 (36%)
LRR_8 932..990 CDD:290566 19/57 (33%)
leucine-rich repeat 933..956 CDD:275380 8/22 (36%)
TIR 1114..1247 CDD:214587
lrrc17XP_009298620.1 LRR_8 72..129 CDD:290566 16/56 (29%)
leucine-rich repeat 72..94 CDD:275380 7/21 (33%)
LRR_4 94..>129 CDD:289563 9/34 (26%)
leucine-rich repeat 95..118 CDD:275380 6/22 (27%)
leucine-rich repeat 119..142 CDD:275380 3/22 (14%)
leucine-rich repeat 143..190 CDD:275380 10/46 (22%)
LRRCT 151..201 CDD:214507 12/49 (24%)
leucine-rich repeat 191..228 CDD:275380 5/36 (14%)
leucine-rich repeat 229..258 CDD:275380 8/97 (8%)
leucine-rich repeat 259..281 CDD:275380 8/21 (38%)
LRR_8 260..316 CDD:290566 20/55 (36%)
leucine-rich repeat 282..305 CDD:275380 8/22 (36%)
leucine-rich repeat 306..329 CDD:275380 7/22 (32%)
TPKR_C2 338..389 CDD:301599 3/6 (50%)
Blue background indicates that the domain is not in the aligned region.


Information from Original Tools:


Tool Simple Score Weighted Score Original Tool Information
BLAST Result Score Score Type Cluster ID
Compara 00.000 Not matched by this tool.
Domainoid 00.000 Not matched by this tool.
eggNOG 00.000 Not matched by this tool.
Hieranoid 00.000 Not matched by this tool.
Homologene 00.000 Not matched by this tool.
Inparanoid 00.000 Not matched by this tool.
OMA 00.000 Not matched by this tool.
OrthoDB 00.000 Not matched by this tool.
OrthoFinder 00.000 Not matched by this tool.
OrthoInspector 00.000 Not matched by this tool.
orthoMCL 00.000 Not matched by this tool.
Panther 1 1.100 - - O PTHR45836
Phylome 00.000 Not matched by this tool.
RoundUp 00.000 Not matched by this tool.
SonicParanoid 00.000 Not matched by this tool.
SwiftOrtho 00.000 Not matched by this tool.
TreeFam 00.000 Not matched by this tool.
ZFIN 00.000 Not matched by this tool.
11.100

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