Protein Alignment Toll-6 and Lrrc3b

DIOPT Version :10

• Sequence 1: NP_524081.1
• Gene: Toll-6 / 39663
• FlyBaseID: FBgn0036494
• Length: 1514
• Species: Drosophila melanogaster
• Sequence 2: NP_666164.1
• Gene: Lrrc3b / 218763
• MGIID: 2384996
• Length: 259
• Species: Mus musculus
• Alignment Length: 210
• Identity: 52/210 - (24%)
• Similarity: 75/210 - (35%)
• Gaps: 62/210 - (29%)

  Fly   826 CPTNCTCFHDQTWSTNIVECSGAAYSEMPRRVPMDTSELYIDGNNFVELAGHSFLGRKNLAVLYA 890
            ||..|.|  ..:...| |.||.|...|:||.:|.:|..||:|.|
Mouse    34 CPKGCLC--SSSGGLN-VTCSNANLKEIPRDLPPETVLLYLDSN--------------------- 74

  Fly   891 NNSNVAHIYNTTFSGLKRLLILHLEDNHIISLEGNEFHNL-ENLRELYLQSNKIASIANGSFQML 954
               .:..|.|..|..|.:|.:|:|..|.|..::.:.|..: |.|:.|.|..|:|.|:...:|..|
Mouse    75 ---QITSIPNEIFKDLHQLRVLNLSKNGIEFIDEHAFKGVAETLQTLDLSDNRIQSVHKNAFNNL 136

  Fly   955 RKLEVLRLDGNRLMHFEVWQLSANPYLVEISLADNQWSCECGYLARFRNYLGQSSEKIIDASRVS 1019
            :                          ....:|:|.|.|:|    ..:..|...:.....|..|.
Mouse   137 K--------------------------ARARIANNPWHCDC----TLQQVLRSMASNHETAHNVI 171

  Fly  1020 CIYNNATSVLREKNG 1034
            |    .||||.|..|
Mouse   172 C----KTSVLDEHAG 182

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-6	NP_524081.1	PPP1R42	<135..>242	CDD:455733
		leucine-rich repeat	148..171	CDD:275380
		leucine-rich repeat	172..201	CDD:275380
		LRR_8	200..>246	CDD:404697
		leucine-rich repeat	202..278	CDD:275380
		leucine-rich repeat	229..249	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR	299..654	CDD:443914
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	402..425	CDD:275380
		leucine-rich repeat	426..449	CDD:275380
		leucine-rich repeat	450..473	CDD:275380
		leucine-rich repeat	474..497	CDD:275380
		leucine-rich repeat	498..518	CDD:275380
		leucine-rich repeat	521..544	CDD:275380
		leucine-rich repeat	545..566	CDD:275380
		leucine-rich repeat	569..592	CDD:275380
		leucine-rich repeat	593..615	CDD:275380
		leucine-rich repeat	616..637	CDD:275380
		leucine-rich repeat	638..662	CDD:275380
		LRR_8	662..719	CDD:404697
		leucine-rich repeat	663..684	CDD:275380
		leucine-rich repeat	685..708	CDD:275380
		leucine-rich repeat	709..728	CDD:275380
		LRR	<863..>990	CDD:443914	24/127 (19%)
		leucine-rich repeat	885..908	CDD:275380	4/22 (18%)
		leucine-rich repeat	909..932	CDD:275380	6/23 (26%)
		leucine-rich repeat	933..956	CDD:275380	8/22 (36%)
		TIR	1114..1247	CDD:214587
Lrrc3b	NP_666164.1	LRRNT	33..68	CDD:214470	14/36 (39%)
		LRR 1	65..86		8/44 (18%)
		leucine-rich repeat	66..89	CDD:275378	9/46 (20%)
		LRR_8	69..125	CDD:404697	19/79 (24%)
		LRR 2	89..110		6/20 (30%)
		leucine-rich repeat	90..113	CDD:275378	6/22 (27%)
		LRR 3	114..135		7/20 (35%)
		leucine-rich repeat	115..138	CDD:275378	8/48 (17%)