| Sequence 1: | NP_001246765.1 | Gene: | Toll-6 / 39663 | FlyBaseID: | FBgn0036494 | Length: | 1514 | Species: | Drosophila melanogaster |
|---|---|---|---|---|---|---|---|---|---|
| Sequence 2: | NP_001381482.1 | Gene: | TLR6 / 10333 | HGNCID: | 16711 | Length: | 796 | Species: | Homo sapiens |
| Alignment Length: | 1124 | Identity: | 209/1124 - (18%) |
|---|---|---|---|
| Similarity: | 354/1124 - (31%) | Gaps: | 485/1124 - (43%) |
- Green bases have known domain annotations that are detailed below.
|
Fly 205 LDLSSNNIWSLPDNIFCTLSELSALNMSENRLQ--DVNELGFRDRSKEPTNGSTESTSTTESAKK 267
Fly 268 SSSSSTSCSLDLEYLDVSH---------------------NDFVVLP-ANGFGTLRRLRVLSVNN 310
Fly 311 NGISM-----IADKALS----GLKN----------LQILNLSSNKIVALPTELFAEQAKI----I 352
Fly 353 QEVYLQNNSISVLNPQLFSN-LDQL----QALDLSMNQITSTWIDKNTFVGLIR----------- 401
Fly 402 -LVLLNLSHNKLTKLEPEIFSDLYTLQILNLRH--NQL----ENIAADTFAPMNNLHTLLLSHNK 459
Fly 460 LKYLDAYALNGLYVLSLLSLDNNALIGVHPDA-FRNCSALQDLNLNGNQLKTVPLALRNMRHLRT 523
Fly 524 VDLGENMITVMEDSAFKGLGNLYGLRLIGNYLENITMHTFRDLPNLQILNLARNRIAVVEPGAFE 588
Fly 589 MTSSIQAVRLDGNELNDINGLFSNMPSLLWLNISDNRLESFDYGHVPSTLQWLDLHKNRLSSLSN 653
Fly 654 R-FGLDSELKLQTLDVSFNQLQRIGPSSIPNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYAN 717
Fly 718 QITTLDIKSLRILPVWEHRALPEFYIGGNPFTCDCNI-DWLQKINHITSRQYPRIMDLETIYCKL 781
Fly 782 LNNRERAYIPLIEAEPKHFLCTYKTHCFAVCHCCEFDACDCEMTCPTNCTCFHDQTWSTNIVECS 846
Fly 847 GAAYSEMPRRVPMDTSELYIDGNNFVELAGHSFLGRKNLAVLYANNSNVAHIYNTTFSGLKRLLI 911
Fly 912 LHLEDNHIISLEGNEFHNLENLRELYLQSNKIASIANGSFQMLRKLEVLRLDGNRLMHFEVWQLS 976
Fly 977 ANPYLVEISLADNQWSCECGYLARFRNYLGQSSEKIIDASRVS--CIYNNATSVLREKNGTKCTL 1039
Fly 1040 RDGVAHYMHTNEIEGLLPLLLVATCAFVAFFGLIFGLFCYRHELKIWAHSTNCLMNFCYKSPRFV 1104
Fly 1105 DQLDKERPNDAYFAYSLQDEHFVNQILAQTLENDIGYRLCLHYRDVNINAYITDALIEAAESAKQ 1169
Fly 1170 FVLVLSKNFLYNEWSRFEYKSALHELV-KRRKRVVFILYGDLPQRDIDMDMRHYLRT----STCI 1229
Fly 1230 EWDDKK-----FWQKLRLA 1243 |
| Gene | Sequence | Domain | Region | External ID | Identity |
|---|---|---|---|---|---|
| Toll-6 | NP_001246765.1 | leucine-rich repeat | 148..171 | CDD:275380 | |
| LRR_8 | 171..236 | CDD:290566 | 13/30 (43%) | ||
| leucine-rich repeat | 172..201 | CDD:275380 | |||
| leucine-rich repeat | 202..278 | CDD:275380 | 17/74 (23%) | ||
| leucine-rich repeat | 229..249 | CDD:275380 | 7/21 (33%) | ||
| LRR_RI | 278..468 | CDD:238064 | 66/257 (26%) | ||
| leucine-rich repeat | 279..302 | CDD:275380 | 15/44 (34%) | ||
| LRR_8 | 301..386 | CDD:290566 | 30/112 (27%) | ||
| leucine-rich repeat | 303..326 | CDD:275380 | 7/31 (23%) | ||
| leucine-rich repeat | 327..350 | CDD:275380 | 12/22 (55%) | ||
| LRR | 350..729 | CDD:227223 | 82/407 (20%) | ||
| leucine-rich repeat | 352..375 | CDD:275380 | 6/23 (26%) | ||
| leucine-rich repeat | 376..401 | CDD:275380 | 7/28 (25%) | ||
| LRR_RI | <401..626 | CDD:238064 | 46/243 (19%) | ||
| leucine-rich repeat | 402..425 | CDD:275380 | 5/22 (23%) | ||
| leucine-rich repeat | 426..449 | CDD:275380 | 7/28 (25%) | ||
| leucine-rich repeat | 450..473 | CDD:275380 | 1/22 (5%) | ||
| leucine-rich repeat | 474..497 | CDD:275380 | 6/23 (26%) | ||
| leucine-rich repeat | 498..518 | CDD:275380 | 1/19 (5%) | ||
| leucine-rich repeat | 521..544 | CDD:275380 | 6/22 (27%) | ||
| leucine-rich repeat | 545..566 | CDD:275380 | 2/20 (10%) | ||
| leucine-rich repeat | 569..592 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 593..615 | CDD:275380 | 2/21 (10%) | ||
| leucine-rich repeat | 616..637 | CDD:275380 | 6/20 (30%) | ||
| leucine-rich repeat | 638..662 | CDD:275380 | 7/24 (29%) | ||
| leucine-rich repeat | 663..684 | CDD:275380 | 7/20 (35%) | ||
| leucine-rich repeat | 685..708 | CDD:275380 | 4/22 (18%) | ||
| leucine-rich repeat | 709..728 | CDD:275380 | 1/18 (6%) | ||
| LRR_8 | 883..943 | CDD:290566 | 2/59 (3%) | ||
| leucine-rich repeat | 885..908 | CDD:275380 | 0/22 (0%) | ||
| leucine-rich repeat | 909..932 | CDD:275380 | 0/22 (0%) | ||
| LRR_8 | 932..990 | CDD:290566 | 8/57 (14%) | ||
| leucine-rich repeat | 933..956 | CDD:275380 | 1/22 (5%) | ||
| TIR | 1114..1247 | CDD:214587 | 40/140 (29%) | ||
| TLR6 | NP_001381482.1 | LRR 1 | 54..77 | 7/19 (37%) | |
| LRR 2 | 78..101 | 8/53 (15%) | |||
| LRR 3 | 102..122 | 7/19 (37%) | |||
| LRR 4 | 123..147 | 8/23 (35%) | |||
| LRR 5 | 148..168 | 3/19 (16%) | |||
| LRR 6 | 169..196 | 8/26 (31%) | |||
| LRR 7 | 197..219 | 8/21 (38%) | |||
| LRR 8 | 220..250 | 7/29 (24%) | |||
| LRR 9 | 251..277 | 7/31 (23%) | |||
| LRR 10 | 278..303 | 5/25 (20%) | |||
| LRR 11 | 304..330 | 6/25 (24%) | |||
| LRR 12 | 331..354 | 3/25 (12%) | |||
| LRR 13 | 355..378 | 8/46 (17%) | |||
| LRR 14 | 379..404 | 9/46 (20%) | |||
| LRR 15 | 405..429 | 7/45 (16%) | |||
| LRR 16 | 430..450 | 5/19 (26%) | |||
| LRR 17 | 451..474 | 7/22 (32%) | |||
| LRR 18 | 475..496 | 7/20 (35%) | |||
| LRR 19 | 497..520 | 4/37 (11%) | |||
| Blue background indicates that the domain is not in the aligned region. | |||||
| Tool | Simple Score | Weighted Score | Original Tool Information | |||
|---|---|---|---|---|---|---|
| BLAST Result | Score | Score Type | Cluster ID | |||
| Compara | 0 | 0.000 | Not matched by this tool. | |||
| Domainoid | 0 | 0.000 | Not matched by this tool. | |||
| eggNOG | 1 | 0.900 | - | - | E2759_KOG4641 | |
| Hieranoid | 0 | 0.000 | Not matched by this tool. | |||
| Homologene | 0 | 0.000 | Not matched by this tool. | |||
| Inparanoid | 0 | 0.000 | Not matched by this tool. | |||
| Isobase | 0 | 0.000 | Not matched by this tool. | |||
| OMA | 0 | 0.000 | Not matched by this tool. | |||
| OrthoDB | 1 | 1.010 | - | - | D147327at33208 | |
| OrthoFinder | 0 | 0.000 | Not matched by this tool. | |||
| OrthoInspector | 0 | 0.000 | Not matched by this tool. | |||
| orthoMCL | 0 | 0.000 | Not matched by this tool. | |||
| Panther | 0 | 0.000 | Not matched by this tool. | |||
| Phylome | 1 | 0.910 | - | - | ||
| RoundUp | 0 | 0.000 | Not matched by this tool. | |||
| SonicParanoid | 1 | 1.000 | - | - | X221 | |
| SwiftOrtho | 0 | 0.000 | Not matched by this tool. | |||
| TreeFam | 0 | 0.000 | Not matched by this tool. | |||
| User_Submission | 0 | 0.000 | Not matched by this tool. | |||
| 4 | 3.820 | |||||