Protein Alignment Toll-6 and si:cabz01090165.1

DIOPT Version :10

• Sequence 1: NP_524081.1
• Gene: Toll-6 / 39663
• FlyBaseID: FBgn0036494
• Length: 1514
• Species: Drosophila melanogaster
• Sequence 2: XP_073784879.1
• Gene: si:cabz01090165.1 / 100333421
• ZFINID: ZDB-GENE-161017-71
• Length: 659
• Species: Danio rerio
• Alignment Length: 335
• Identity: 82/335 - (24%)
• Similarity: 131/335 - (39%)
• Gaps: 114/335 - (34%)

  Fly   477 LSLDNNALIGVHPDAFRNCSALQDLNLNGNQLKTV-PLALRNMRHLRTVDLGENMITVMEDSAFK 540
            |.|.:|.:..:....|.|.|:|..|.|:.|.:..: |.|..:::.|..:.|..|.:||::|:..:
Zfish    79 LRLMDNFITSLRHRDFANMSSLIHLTLSRNTISQIRPYAFADLQDLHALHLDANRLTVLDDTHLQ 143

  Fly   541 GLGNLYGLRLIGNYLENITMHTFRD-LPNLQILNLARNRIAVVEPGAFEMTSSIQAVRLDGNELN 604
            ||.||..|.|..|.:.:|:...|:| |..|:.|:|:.|.:..:......|.:|:..:.||.|.:.
Zfish   144 GLVNLRHLILANNQIHSISEGAFQDFLETLEDLDLSYNNLVDLPWDTIAMLASVNTLSLDHNLIE 208

  Fly   605 DI-NGLFSNMPSLLWLNISDNRLESFDYGHVPSTLQWLDLHKNRLSSLSNRFGLDSELKLQTLDV 668
            .: .|:|||                              ||                 ||..||:
Zfish   209 FVPEGIFSN------------------------------LH-----------------KLARLDM 226

  Fly   669 SFNQLQRIGPSSIPNSIELLFLNDNLITTVDPDTFMHKTNLTRVDLYA----NQITTLDIKSLRI 729
            :.|:|::|.|       :.|||                    |:.:||    :.:|.|.:.
Zfish   227 TSNKLKKIPP-------DPLFL--------------------RIPVYAKMKGSPLTALVLS---- 260

  Fly   730 LPVWEHRALPEFYIGGNPFTCDCNIDWLQKINHITSRQYPRIMDLETIYCKLLNNRERA--YIPL 792
                         .||||..|:|.:.||:::.        |..||||  |  .:.||.|  |...
Zfish   261 -------------FGGNPLHCNCELVWLRRLT--------REDDLET--C--ASPRELAGKYFWT 300

  Fly   793 IEAEPKHFLC 802
            |..|  .|:|
Zfish   301 IREE--EFVC 308

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Toll-6	NP_524081.1	PPP1R42	<135..>242	CDD:455733
		leucine-rich repeat	148..171	CDD:275380
		leucine-rich repeat	172..201	CDD:275380
		LRR_8	200..>246	CDD:404697
		leucine-rich repeat	202..278	CDD:275380
		leucine-rich repeat	229..249	CDD:275380
		leucine-rich repeat	279..302	CDD:275380
		LRR	299..654	CDD:443914	44/179 (25%)
		leucine-rich repeat	303..326	CDD:275380
		leucine-rich repeat	327..350	CDD:275380
		leucine-rich repeat	352..375	CDD:275380
		leucine-rich repeat	376..401	CDD:275380
		leucine-rich repeat	402..425	CDD:275380
		leucine-rich repeat	426..449	CDD:275380
		leucine-rich repeat	450..473	CDD:275380
		leucine-rich repeat	474..497	CDD:275380	5/19 (26%)
		leucine-rich repeat	498..518	CDD:275380	6/20 (30%)
		leucine-rich repeat	521..544	CDD:275380	8/22 (36%)
		leucine-rich repeat	545..566	CDD:275380	7/21 (33%)
		leucine-rich repeat	569..592	CDD:275380	5/22 (23%)
		leucine-rich repeat	593..615	CDD:275380	7/22 (32%)
		leucine-rich repeat	616..637	CDD:275380	0/20 (0%)
		leucine-rich repeat	638..662	CDD:275380	2/23 (9%)
		LRR_8	662..719	CDD:404697	14/60 (23%)
		leucine-rich repeat	663..684	CDD:275380	7/20 (35%)
		leucine-rich repeat	685..708	CDD:275380	3/22 (14%)
		leucine-rich repeat	709..728	CDD:275380	5/22 (23%)
		LRR	<863..>990	CDD:443914
		leucine-rich repeat	885..908	CDD:275380
		leucine-rich repeat	909..932	CDD:275380
		leucine-rich repeat	933..956	CDD:275380
		TIR	1114..1247	CDD:214587
si:cabz01090165.1	XP_073784879.1	None