DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and PUT4

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_014993.1	Gene:	PUT4 / 854530	SGDID:	S000005875	Length:	627	Species:	Saccharomyces cerevisiae

Alignment Length:	426	Identity:	97/426 - (22%)
Similarity:	166/426 - (38%)	Gaps:	68/426 - (15%)

- Green bases have known domain annotations that are detailed below.

  Fly    15 KNLQADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMISFAIAA----- 74
            |:...||.....||.:.|....:..:.:|..:|.|:.|.............:.||:.|.:
Yeast    93 KSPSVDGDSEPHKLKQGLQSRHVQLIALGGAIGTGLLVGTSSTLHTCGPAGLFISYIIISAVIYP 157

  Fly    75 -LASLLAGVCYAEFGARVPKAGSA--YVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYL 136
             :.:|...||:.. |.....|||.  .|..||  ...:.|..|||....|||..|:.|...|
Yeast   158 IMCALGEMVCFLP-GDGSDSAGSTANLVTRYV--DPSLGFATGWNYFYCYVILVAAECTAAS--- 216

  Fly   137 DSLLNDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCL-NIFIL 200
                 ..::| :....|..|...    .||...:::.|.....:|......|:..:.|: .:.||
Yeast   217 -----GVVEY-WTTAVPKGVWIT----IFLCVVVILNFSAVKVYGESEFWFASIKILCIVGLIIL 271

  Fly   201 GFVIIAGA----LKADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFV-GFDCIA 260
            .|::..|.    .:..:..|. .|...:.:.|.||.|.|...:.|.::||    |.|: |.:.:.
Yeast   272 SFILFWGGGPNHDRLGFRYWQ-HPGAFAHHLTGGSLGNFTDIYTGIIKGA----FAFILGPELVC 331

  Fly   261 TTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQD---VNA-----------PLP 311
            .|..|..:.|:||.|:....:..:...|...:..:::::||  .|   |||           |..
Yeast   332 MTSAECADQRRNIAKASRRFVWRLIFFYVLGTLAISVIVPY--NDPTLVNALAQGKPGAGSSPFV 394

  Fly   312 YAFEYVGWPVAMWIVTVGGLVGLLASLFGA----LFPLPRVMYSMAQDGLLFKFLGKVSPRFRVP 372
            ...:..|..|...|  :.|.:  |.|.:.|    :|...|.:.:|||.|...|.||::: ::.||
Yeast   395 IGIQNAGIKVLPHI--INGCI--LTSAWSAANAFMFASTRSLLTMAQTGQAPKCLGRIN-KWGVP 454

  Fly   373 VTGSIVAAL--------FTAAIAGLFDLSQLVSLLS 400
            .....|:.|        .:::.|.:|:....:|.:|
Yeast   455 YVAVGVSFLCSCLAYLNVSSSTADVFNWFSNISTIS 490

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	97/426 (23%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
PUT4	NP_014993.1	2A0310	107..593	CDD:273334	92/412 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.950