DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and TAT2

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_014622.1	Gene:	TAT2 / 854139	SGDID:	S000005380	Length:	592	Species:	Saccharomyces cerevisiae

Alignment Length:	525	Identity:	123/525 - (23%)
Similarity:	200/525 - (38%)	Gaps:	139/525 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGP-SVMISFAIAALASLLAGVC 83
            |||...:.|.|.|....|..:.:|.::|.|::|.:|: |..:.|| .|:|.:|||  .|.:.|..
Yeast    70 DGSFDTSNLKRTLKPRHLIMIAIGGSIGTGLFVGSGK-AIAEGGPLGVVIGWAIA--GSQIIGTI 131

  Fly    84 Y--AEFGARVPKAGSAYVYSYVCIGEFVAFVIG------WNLILEYVIGTASVCRGISLYLDSLL 140
            :  .|...|.|..|:...|....:...::||:.      |..:|...|..|::
Yeast   132 HGLGEITVRFPVVGAFANYGTRFLDPSISFVVSTIYVLQWFFVLPLEIIAAAM------------ 184

  Fly   141 NDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFG-VETSTMANNFVTCLNIFILGFVI 204
              |::|..:.:.|  |.::..::..:.  .:.:|||. .|| .|.:......:|.....||..|:
Yeast   185 --TVQYWNSSIDP--VIWVAIFYAVIV--SINLFGVR-GFGEAEFAFSTIKAITVCGFIILCVVL 242

  Fly   205 IAGA------LKADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFD--CIAT 261
            |.|.      :.|.|  |. ||..: ||           ||.|.|.......:...|.:  |:|
Yeast   243 ICGGGPDHEFIGAKY--WH-DPGCL-AN-----------GFPGVLSVLVVASYSLGGIEMTCLA- 291

  Fly   262 TGEEVRNPRKNIP---KSILLSLLIIFLCYFGVSTVLTLMLPYYIQDV-------NAPLPYAFEY 316
            :||  .:| |.:|   |.:...:|..||...   |::..::||..|::       |:|...|.:.
Yeast   292 SGE--TDP-KGLPSAIKQVFWRILFFFLISL---TLVGFLVPYTNQNLLGGSSVDNSPFVIAIKL 350

  Fly   317 VGWPVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAAL 381
            ........||....|:.:|:.....:|...|.:.|||..||:..:.|.:....| |:.|.:..:|
Yeast   351 HHIKALPSIVNAVILISVLSVGNSCIFASSRTLCSMAHQGLIPWWFGYIDRAGR-PLVGIMANSL 414

  Fly   382 F------------------TAAIAGL--------------------------FDLSQLVSLLSI- 401
            |                  ..|||||                          .|..:.||.:.|
Yeast   415 FGLLAFLVKSGSMSEVFNWLMAIAGLATCIVWLSINLSHIRFRLAMKAQGKSLDELEFVSAVGIW 479

  Fly   402 GTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSER---FTFGSVCTQ----LF 459
            |:  |||.: |:.::|....||.:....|           .||..||   |....:|..    :|
Yeast   480 GS--AYSAL-INCLILIAQFYCSLWPIGG-----------WTSGKERAKIFFQNYLCALIMLFIF 530

  Fly   460 NVHRV 464
            .||::
Yeast   531 IVHKI 535

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	123/525 (23%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
TAT2	NP_014622.1	LysP	52..591	CDD:223903	123/525 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	90	1.000	Inparanoid score	I1545
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	1.950