DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and UGA4

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_010071.1	Gene:	UGA4 / 851317	SGDID:	S000002369	Length:	571	Species:	Saccharomyces cerevisiae

Alignment Length:	523	Identity:	116/523 - (22%)
Similarity:	191/523 - (36%)	Gaps:	141/523 - (26%)

- Green bases have known domain annotations that are detailed below.

  Fly    31 VLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMI-SFAIAALASLLAGVCYAEFGARVPKA 94
            ::||..    .:.|.:|.|   |.|       ||:.:: .:.:||...||.|:..||..:.:|.|
Yeast    86 IMGLLP----SIASVMGGG---LGG-------GPATLVWGWFVAAFFILLVGITMAEHASSIPTA 136

  Fly    95 GSAYVYSYVC----IGEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLLNDTLKYTFAEVAPMN 155
            |..|.::|..    ..|.::|:||.:..|....|..|:..|::..:.:.:..|....| ||..
Yeast   137 GGLYYWTYYYAPEGYKEIISFIIGCSNSLALAAGVCSIDYGLAEEIAAAVTLTKDGNF-EVTS-- 198

  Fly   156 VSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGALKADYSNWTVDP 220
                |..:...| |.|||..:...................|:||:..:.||
Yeast   199 ----GKLYGIFA-GAVVVMCICTCVASGAIARLQTLSIFANLFIIVLLFIA-------------- 244

  Fly   221 STVSANSTIGS----GGF----FPFGFEGTL----RGAATCFFGFV-------GFDCIATTGEEV 266
                  ..||:    |||    |.||....|    .|...|..||:       .||......||.
Yeast   245 ------LPIGTKHRMGGFNDGDFIFGKYENLSDWNNGWQFCLAGFMPAVWTIGSFDSCVHQSEEA 303

  Fly   267 RNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVNAPLPYAFEYVGWPVAM-------- 323
            ::.:|::|..|:.|:.:   |:.....::..::.....|:::.|...:   |:.:|.
Yeast   304 KDAKKSVPIGIISSIAV---CWILGWLIIICLMACINPDIDSVLDSKY---GFALAQIIYDSLGK 362

  Fly   324 -WIVTVGGLVGLLASLFGALF--PLPRVMYSMAQD-GL-LFKFLGKVSPRFRVPVTGSIVAALFT 383
             |.:....|:.....|.||..  .:.|.:::.::| || |.|::.:|..::.||.. :|:||...
Yeast   363 KWAIAFMSLIAFCQFLMGASITTAVSRQVWAFSRDNGLPLSKYIKRVDSKYSVPFF-AILAACVG 426

  Fly   384 AAIAGLFDL------SQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSL 442
            :.|.||..|      ..|.||...|..||:|...:                           ..|
Yeast   427 SLILGLLCLIDDAATDALFSLAVAGNNLAWSTPTV---------------------------FRL 464

  Fly   443 TSSSERFTFG---------------SVCTQLFNVHRVQEPNAISSRIVGVLSTLF---CLISLGI 489
            ||..:.|..|               .|..|||.:..|..|    |:..|:..:..   |:|..||
Yeast   465 TSGRDLFRPGPFYLGKIWSPIVAWTGVAFQLFIIILVMFP----SQQHGITKSTMNYACVIGPGI 525

  Fly   490 GVL 492
            .:|
Yeast   526 WIL 528

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	116/523 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
UGA4	NP_010071.1	2A0304	61..529	CDD:273331	116/523 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	74	1.000	Domainoid score	I2150
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	1	1.000	-	-		otm46571
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	2	2.000