DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and CAT3

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_198510.2	Gene:	CAT3 / 833664	AraportID:	AT5G36940	Length:	609	Species:	Arabidopsis thaliana

Alignment Length:	640	Identity:	222/640 - (34%)
Similarity:	349/640 - (54%)	Gaps:	67/640 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LTRRKNLQADGSEGET-----KLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMISF 70
            |.|||...:...:.||     :|.:.|....|.|:|||||:|||||:|.|.:|::.:||::.:||
plant     7 LVRRKQFDSSNGKAETHHHHQQLAKALTFPHLIAIGVGSTIGAGVYILVGTVAREHSGPALALSF 71

  Fly    71 AIAALASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLY 135
            .||.:::.|:..||||..:|.|.|||||.|||:||||.||::|||.|||||.||.::|.||||..
plant    72 LIAGISAALSAFCYAELSSRFPSAGSAYHYSYICIGEGVAWLIGWALILEYTIGGSTVARGISPN 136

  Fly   136 LDSLL--NDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIF 198
            |..:.  .|.|....|.   ..:..|....|..|..||.:.......||:.||.|...||..|:|
plant   137 LAMIFGGEDCLPTILAR---HQIPGLDIVVDPCAAVLVFIVTGLCCLGVKESTFAQGIVTTANVF 198

  Fly   199 ILGFVIIAGALKADYSNWTVDPSTVSANSTIG---SGGFFPFGFEGTLRGAATCFFGFVGFDCIA 260
            ::.|||:||:.....:.|            :|   ..|:||:|.:|.|.|:||.||.::|||.:|
plant   199 VMIFVIVAGSYLCFKTGW------------VGYELPTGYFPYGVDGMLTGSATVFFAYIGFDTVA 251

  Fly   261 TTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVNAPLPYAFEYVGWPVAMWI 325
            :..|||:|||:::|..|.:|||:..|.|..||.|:..::|||..|.:.|:..||...|...|.::
plant   252 SMAEEVKNPRRDLPLGIGISLLLCCLLYMMVSVVIVGLVPYYAMDPDTPISSAFSSHGIQWAAYL 316

  Fly   326 VTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLF 390
            :.:|.::.|.::|.|::.|.||::.:||:||||..:...|:.|.:||:.|:|...:..|.:|...
plant   317 INLGAVMALCSALMGSILPQPRILMAMARDGLLPSYFSYVNQRTQVPINGTITTGVCAAILAFFM 381

  Fly   391 DLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSS--SERFTFGS 453
            |:|||..::|:|||:|:::||||::::||:  ...||.|....::.:.::.:.:|  |::...|.
plant   382 DVSQLAGMVSVGTLVAFTMVAISLLIVRYV--VPPDEVPLPSSLQENSSSHVGTSIRSKQPLLGK 444

  Fly   454 VCTQLFNVHRVQEPNAISSRIVGV--------LSTLF-C----LISLGIGVLIMQAHLLIASKEV 505
            |...:     |.:.||..|.::..        .|.:| |    |:|......::...|..:...|
plant   445 VDDSV-----VDKENAPGSWVLNKKNRRKFAGWSIMFTCIGNFLLSYAASSFLLPGLLRYSLCGV 504

  Fly   506 WALTLLIVLVVLMLLVICLICLQPREARRRL-----FRVPFVPIVPAISIFINIYLMLQLDTWTW 565
            ..|.||:.|:|       |||:...:||...     |..||||::|.:.|.||:||::.|...||
plant   505 GGLFLLVGLIV-------LICIDQDDARHSFGHSGGFICPFVPLLPIVCILINMYLLVNLGAATW 562

  Fly   566 IRFGVWMIVGIPVFLACWYLYDCKNPAKRNPERWDFYKALKGLQESREQEYHCIS 620
            :|..||:.:|:.|::    .|..:|.:..|.    .|.:...|||.|....|.::
plant   563 VRVSVWLFLGVVVYI----FYGRRNSSLVNA----VYVSTAHLQEIRRTSGHSLA 609

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	213/599 (36%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617	19/42 (45%)
CAT3	NP_198510.2	2A0303	5..584	CDD:273330	214/609 (35%)
CAT3	NP_198510.2	AA_permease_C	534..584	CDD:290617	20/53 (38%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	1	1.000	307	1.000	Domainoid score	I322
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	1	1.000	-	-		H20659
Inparanoid	1	1.050	352	1.000	Inparanoid score	I609
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D439017at2759
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	1	1.000	-	-		mtm1003
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	1	1.000	-	-
TreeFam	1	0.960	-	-
	13	12.830