DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and si:dkeyp-120h9.1

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_001093492.1	Gene:	si:dkeyp-120h9.1 / 566469	ZFINID:	ZDB-GENE-070705-534	Length:	487	Species:	Danio rerio

Alignment Length:	547	Identity:	123/547 - (22%)
Similarity:	219/547 - (40%)	Gaps:	121/547 - (22%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GSEGETKLNRVLGLWDLTALGVGSTLGAGVYVL-AGQIAKDQAGPSVMISFAIAALASLLAGVCY 84
            ||....:|.:.:.|.....|.||:.:|:|::|. .|.:.|..:....::.:||..:.|:...:||
Zfish     5 GSTSSMRLKQEISLLHGVCLIVGNMIGSGIFVSPIGVLEKTGSYGLSLVVWAIGGIFSVFGALCY 69

  Fly    85 AEFGARVPKAGSAYVYSYVCIGEFVAFVIGWN--LILEYVIGTASVCRGISLYLDSLLNDTLKYT 147
            ||.|..:.|:|::|.|.....|.|:||:..|.  :|:|      ..|:.:           :..|
Zfish    70 AELGTTIRKSGASYAYILETFGGFLAFIRLWTSLMIVE------PACQAV-----------IALT 117

  Fly   148 FAE--VAPMNVSFLGSY-----FDFLAFGLVVV-------FGVALAFGVETSTMANNFVTCLNIF 198
            ||.  |.|...:....|     ...|..||:.:       :|..|..   .||:| ..:..:.|.
Zfish   118 FANYLVKPFFPTCPAPYDAVRLIAALIIGLLTIVNCMKVKWGAILQV---ISTVA-KVLALIVII 178

  Fly   199 ILGFVIIA----GALKADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCI 259
            |.|.|::|    ...:..:.|..:||..:|.                   ......:.:.|:|.:
Zfish   179 IAGMVVLAQGETNNFRDSFENSKLDPGNMSL-------------------ALYAALYSYSGWDTL 224

  Fly   260 ATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVNAPL----------PYAF 314
            ....||::||.:|:|.||.:|:.|:.:.|     :||.:..|.:.|:|..|          .|..
Zfish   225 NFITEEIKNPERNLPLSIAISMPIVTIIY-----ILTNVAYYAVLDMNTLLQSEAVAVTFADYVL 284

  Fly   315 EYVGW--PVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSI 377
            .|..|  |:::.|...|   ||.:|:..|    .|:.:..:::|.|...|..:..:...|    |
Zfish   285 GYASWLIPLSVAISCYG---GLNSSIIAA----SRLFFVGSREGHLPNVLCMIHVKRYTP----I 338

  Fly   378 VAALFTAAIAGLF----DLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASE 438
            .|.||...::.::    |:.||::..|....|...:...|.:.||:    :..:.|  |.::.|
Zfish   339 PALLFNGGMSLIYLCVRDVFQLINYFSFNYWLFIGLSIGSQIYLRF----KAPDMP--RPIKLS- 396

  Fly   439 TTSLTSSSERFTFGSVCTQLFNVHRVQEP---NAISSRIVGVLSTLFCLISLGIGVLIMQAHLLI 500
                       .|..:...|.:|..|..|   :.|:| :||:...|     .|..|..:..||..
Zfish   397 -----------LFFPIVYCLCSVFLVVVPLYSDTINS-LVGIAVAL-----SGAPVYYICVHLPP 444

  Fly   501 ASKEVWALTLLIVLVVLMLLVICLICL 527
            :|:..: |..::....|....:|..|:
Zfish   445 SSRPAF-LGQMLDTFSLQTQKLCYCCV 470

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	123/547 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
si:dkeyp-120h9.1	NP_001093492.1	2A0308	12..466	CDD:273332	119/534 (22%)
si:dkeyp-120h9.1	NP_001093492.1	SLC5-6-like_sbd	16..>263	CDD:294310	68/291 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593004
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930