DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and CG1607

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_001263139.1	Gene:	CG1607 / 43707	FlyBaseID:	FBgn0039844	Length:	507	Species:	Drosophila melanogaster

Alignment Length:	549	Identity:	117/549 - (21%)
Similarity:	223/549 - (40%)	Gaps:	115/549 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVL-AGQIAKDQAGPSVMISFAIAALASLLAGVC 83
            ||. ||..|...:.|.:...:.|||.:|:|::|. .|.:....:....:|.:.|:.|.|::...|
  Fly    38 DGG-GEVTLKAKMSLLNGCTVIVGSIIGSGIFVSPTGVLMYTGSVNLALIVWVISGLFSMVGAYC 101

  Fly    84 YAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVI----GTASVCRGISLYLDSLLNDTL 144
            |||.|..:.|:|:.|.|.....|.|:||:..|   :|.:|    ..|.|....|.|:       |
  Fly   102 YAELGTMITKSGADYAYIMETFGPFMAFIRLW---IECMIVRPCSQAIVALTFSTYV-------L 156

  Fly   145 KYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGAL 209
            |..|.|..|...|     ...||...::|..:...:.|:.:|...:..|...:..| |:|||..:
  Fly   157 KPFFPECTPPEDS-----ARLLAVCCILVLTLINCWDVKWATAVQDIFTYAKLLAL-FIIIATGV 215

  Fly   210 KADYSNWTVDPSTVSANSTIGSGGFFPFGFEGT---LRGAATCF----FGFVGFDCIATTGEEVR 267
            ...|               :|:..:|.  ||.|   :...|..|    |.:.|::.:....||::
  Fly   216 YQLY---------------LGNTQYFT--FENTDTKVTSIALSFYSGLFAYNGWNYLNFIIEELK 263

  Fly   268 NPRKNIPKSILLSLLIIFLCYFGVS-TVLTLMLPYYIQDVNA-PLPY---AFEYVGW--PVAMWI 325
            :|.||:|::|.:|..::.:.|...: :..|::.|..:...:| .:.|   ||..:.|  ||.:.:
  Fly   264 DPVKNLPRAIAISCTLVTIVYVMANVSFYTILSPDEVMGSSAVAVTYAERAFGMLAWTIPVFVAL 328

  Fly   326 VTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLF 390
            .|.|.:.|:|.:       ..|:.|:.|.:|.:.:.|..:..:...|....:..||.:.....:.
  Fly   329 STFGAVNGILLT-------SSRLFYAGANNGQMPEILTMIQIQRFTPTPAVLAMALLSMLYLTVS 386

  Fly   391 DLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSERFTFGSVC 455
            |:..|::.:...|.|:..|..:.:..||:       ..|
  Fly   387 DIFALINYVGFATWLSIGVAVLCLPWLRW-------AQP-------------------------- 418

  Fly   456 TQLFNVHR-VQEPNAISSRIVGVLSTLFCL--------ISLGIGVLIMQAHLLI-------ASKE 504
                |:.| ::.|....  ||.:::|:|..        :..|.|:|::.:.:.:       .:|.
  Fly   419 ----NLPRPIRVPMVFP--IVYLIATIFVTVVPMYASPVETGYGILMILSSIPVYLVFIAWKNKP 477

  Fly   505 VWALTLLIVLVVLMLLVICLICLQPREAR 533
            :|....::.|...:..::.::..|.:.|:
  Fly   478 IWFQKTMVSLTRFLQKMLMVLGKQTKPAQ 506

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	117/549 (21%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
CG1607	NP_001263139.1	2A0308	42..501	CDD:273332	112/537 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466564
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840