DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and mnd

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_524074.1	Gene:	mnd / 39625	FlyBaseID:	FBgn0002778	Length:	499	Species:	Drosophila melanogaster

Alignment Length:	496	Identity:	110/496 - (22%)
Similarity:	213/496 - (42%)	Gaps:	66/496 - (13%)

- Green bases have known domain annotations that are detailed below.

  Fly    16 NLQAD-GSEGE-TKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAK--DQAGPSVMISFAIAALA 76
            |..|| ||:|. .||.:.:||.|..|:.||..:|:|::|....:.|  ...|.|::: :.::.:.
  Fly    25 NSTADSGSQGSGVKLKKQIGLLDGVAIIVGVIVGSGIFVSPKGVLKFSGSIGQSLIV-WVLSGVL 88

  Fly    77 SLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYV-IGTASVCRGISLYLDSLL 140
            |::..:||||.|..:||:|..|.|.....|...||:..|..:|..| .|.|......::||
  Fly    89 SMVGALCYAELGTMIPKSGGDYAYIGTAFGPLPAFLYLWVALLILVPTGNAITALTFAIYL---- 149

  Fly   141 NDTLKYTFAEV-APMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVI 204
               ||..:... ||:..      ...||..::.|..:...:.|:..|...:..|...:..|..::
  Fly   150 ---LKPFWPSCDAPIEA------VQLLAAAMICVLTLINCYNVKWVTRVTDIFTGTKVVALLVIV 205

  Fly   205 IAGALKADYSNWTVDPSTVSANSTIGSG----GFFPFGFEGTLRGAATCFFGFVGFDCIATTGEE 265
            .||..      |..|.:|...::....|    |:....|...|       |.:.|::.:....||
  Fly   206 GAGVW------WLFDGNTEHWDNPFSGGLQDPGYIALAFYSGL-------FSYSGWNYLNFVTEE 257

  Fly   266 VRNPRKNIPKSILLSLLIIFLCYFGVSTV--LTLMLPYYIQDVNA-PLPYAFEYVGWPVAMWIVT 327
            :::|.:|:||:|.:|:.::.:.|. ::.:  .:::.|..|...:| .:.:..:.:|:  ..||:.
  Fly   258 LKDPYRNLPKAICISMPVVTVIYM-ITNIAYFSVLSPDEILSSDAVAVTFGDKMLGY--MSWIMP 319

  Fly   328 VGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLFDL 392
            .........||.||:|...|:.:..|::|.|...:..::.....||...|...:.|..:..:.|:
  Fly   320 FAVACSTFGSLNGAIFASSRLFFVGARNGHLPAAISLINVNCLTPVPSLIFLGVLTLLLLFIEDV 384

  Fly   393 SQLVSLLSIGTLLAYSVVAIS-IMLLRYMDYCEVDENPGQREVRASETTSLTSSSERFTFGSVCT 456
            ..|::.:|....| ::::::| ::.:||      .:...:|.::.:....:       .:..||.
  Fly   385 YVLINYVSYVEAL-FTLISVSGLLWMRY------KQPKTERPIKVNLALPI-------IYLIVCL 435

  Fly   457 QLFNVHRVQEPNAISSRIVGVLSTLFCLISLGIGVLIMQAH 497
            .|......|.|..:....:.:||        ||.|..:..|
  Fly   436 FLVIFSCTQTPYVVGIGTIIILS--------GIPVYYLTIH 468

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	110/496 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
mnd	NP_524074.1	2A0308	22..496	CDD:273332	110/496 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C45466579
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
	2	1.840