DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and Slc7a15

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_001033749.1	Gene:	Slc7a15 / 328059	MGIID:	3045351	Length:	488	Species:	Mus musculus

Alignment Length:	508	Identity:	112/508 - (22%)
Similarity:	210/508 - (41%)	Gaps:	55/508 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV-MISFAIAALASLLAG 81
            |..|:.| ..|.|.:|||...::..|..:|:|:::....:......|.. :|.:|...|.::|..
Mouse    18 QGSGTAG-LMLKREIGLWSAVSMTAGCMIGSGIFMSPQGVLVYIGSPGASLIVWATCGLLAMLGA 81

  Fly    82 VCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYV-IGTASVCRGISLYLDSLLNDTLK 145
            :||||.|:.||::|..|.|.....|...||::    |..|| :|..:....:||       ...:
Mouse    82 LCYAELGSLVPESGGDYAYILRTFGSLPAFLV----IYVYVLVGRPAGITAVSL-------SFAE 135

  Fly   146 YTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGALK 210
            |..|...|...|........:|...:::..:...:....||:..|..|...:|.|..:::.||:.
Mouse   136 YVLAPFYPGCSSLPQVIVKIVASSCILLLLLINFWSSRMSTVLMNVCTTAKVFSLLVIVVGGAVV 200

  Fly   211 ADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEEVRNPRKNIPK 275
            ....:.:.:....:.::|....|.....|...|       :.|.|:..|.|..||::||::|:..
Mouse   201 LMQGHASTESLLFAFHNTTQQAGRIGMAFYQGL-------WSFDGWSNINTVIEELKNPKQNLLW 258

  Fly   276 SILLSLLIIFLCYFGVS-TVLTLMLPYYIQDVNA-PLPYAFEYVG-WPVAMWIVTVGGLVGLLAS 337
            :::.::.::.:.|..|: :.|.:|.|..|...:| .:.:....:| |   .|:|.:...:....:
Mouse   259 AVMTAVPLVTILYVLVNISYLLVMSPSEILSSDAIAVIWGDRVLGSW---AWLVPLAVALSTFGT 320

  Fly   338 LFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLF----DLSQLVSL 398
            :.|..|...||.|:.|::|.:.:.:..:......|..    |.:||.|:|.|.    :.|..|:|
Mouse   321 VNGGFFSGSRVCYAAAREGHMPQLMSMIHVNRLTPAP----AQIFTTAVALLLVIPGNFSTFVNL 381

  Fly   399 LSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSERFTFGSVCTQLFNVHR 463
            ||..:.|.|......::.||.                  :|.:|..:.:..||......|.:::.
Mouse   382 LSFLSWLTYGTTFACLLYLRI------------------KTKNLPHTYKVPTFIPAIMLLVSLYL 428

  Fly   464 VQEPNAISSRIVGVLSTLFCLISLGIGVLIMQAHLLIASKEVWALTLLIVLVV 516
            |..|.....:|..:...||.|  .|..|..:..|.....|.:...|:.:.|::
Mouse   429 VLAPIIDHPQIEFLYIFLFVL--SGFPVYFLLFHFQCQFKCIQTATMHLQLLL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	112/508 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
Slc7a15	NP_001033749.1	2A0308	5..481	CDD:273332	112/508 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847662
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930