DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and Slc7a11

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	XP_038958186.1	Gene:	Slc7a11 / 310392	RGDID:	1309275	Length:	505	Species:	Rattus norvegicus

Alignment Length:	394	Identity:	86/394 - (21%)
Similarity:	152/394 - (38%)	Gaps:	51/394 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    42 VGSTLGAGVYVLAGQIAKDQAGPSVMISF-AIAALASLLAGVCYAEFGARVPKAGSAYVYSYVCI 105
            :|:.:|:|:::....|.::.....:.:.| :...:.||...:.|||.|..:.|:|..|.|.....
  Rat    54 IGTVIGSGIFISPKGILQNTGSVGMSLVFWSACGVLSLFGALSYAELGTSIKKSGGHYTYILEVF 118

  Fly   106 GEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLLNDTLKYTFAEVAPMNVSFLGSYFDFLAFGL 170
            |..:|||..|..:|....|..:|   |||.....:             :...|:......||..|
  Rat   119 GPLLAFVRVWVELLVIRPGATAV---ISLAFGRYI-------------LEPFFIQCEIPELAIKL 167

  Fly   171 VVVFGVALAF-----GVETSTMANNFVTCLNIFILGFVIIAGALKADYSNWTVDPSTVSANSTIG 230
            |...|:.:..     .|..|.....|:|...:..:..:|:.|.::.                ..|
  Rat   168 VTAVGITVVMVLNSTSVSWSARIQIFLTFCKLTAILIIIVPGVIQL----------------IKG 216

  Fly   231 SGGFFPFGFEG---TLRGAATCF----FGFVGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLCY 288
            ....|...|.|   .|.|....|    :.:.|:..:....|||.||.|.||.:|.:|:.||.:.|
  Rat   217 QTHHFKDAFSGRDTNLMGLPLAFYYGMYAYAGWFYLNFITEEVDNPEKTIPLAICISMAIITVGY 281

  Fly   289 F--GVSTVLTLMLPYYIQDVNAPLPYAFEYVG-WPVAMWIVTVGGLVGLLASLFGALFPLPRVMY 350
            .  .|:...|:.....:|.....:.::...:| :.:|:.|...   :....|:.|.:|.:.|:.|
  Rat   282 VLTNVAYFTTISAEELLQSSAVAVTFSERLLGKFSLAVPIFVA---LSCFGSMNGGVFAVSRLFY 343

  Fly   351 SMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIM 415
            ..:::|.|.:.|..:......|:...||....|..:....||..|::.||....|...:....::
  Rat   344 VASREGHLPEILSMIHVHKHTPLPAVIVLHPLTMIMLFSGDLYSLLNFLSFARWLFMGLAVAGLI 408

  Fly   416 LLRY 419
            .|||
  Rat   409 YLRY 412

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	86/394 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
Slc7a11	XP_038958186.1	2A0308	1..482	CDD:273332	86/394 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351207
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930