DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and Slc7a15

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_001100184.1	Gene:	Slc7a15 / 298873	RGDID:	1560726	Length:	488	Species:	Rattus norvegicus

Alignment Length:	507	Identity:	114/507 - (22%)
Similarity:	214/507 - (42%)	Gaps:	53/507 - (10%)

- Green bases have known domain annotations that are detailed below.

  Fly    18 QADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV-MISFAIAALASLLAG 81
            |..|:.|.| :.|.:|||...::..|..:|:|:::....:......|.. :|.:|...|.:||..
  Rat    18 QGSGAAGLT-MKREIGLWSAVSMTAGCMIGSGIFMSPQGVLVYIGSPGASLIIWATCGLLALLGA 81

  Fly    82 VCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLLNDTLKY 146
            :||||.|:.||::|..|.|.....|...||::.:.::|   :|..:....:||       ...:|
  Rat    82 LCYAELGSLVPESGGEYAYILRAFGSLPAFLVIYIIVL---VGRPAAITAVSL-------SFAEY 136

  Fly   147 TFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGFVIIAGALKA 211
            ..|...|...|........:|...::|..:...:....||:..|..|...:|.|..:::.||:..
  Rat   137 ALAPFYPGCSSVPQVIVKIVACSCILVLLLINFWSSRMSTVLMNVCTAAKLFSLLVIVVGGAVGL 201

  Fly   212 DYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEEVRNPRKNIPKS 276
            .......:....:.::|....|.....|...|       :.|.|:..|.|..||::||::|:..:
  Rat   202 AQGRIPTESLLFAFHNTTQQAGRIGMAFYQGL-------WSFDGWSNINTVIEEIKNPKQNLVWA 259

  Fly   277 ILLSLLIIFLCYFGVS-TVLTLMLPYYIQDVNA-PLPYAFEYVG-WPVAMWIVTVGGLVGLLASL 338
            :::::.::.:.|..|: :.|.:|.|..|...:| .:.:..:.:| |   .|:|.:...:....::
  Rat   260 VVIAIPLVTILYVLVNISYLLVMSPSEILTSDAIAVTWGNQVLGSW---AWLVPLAVALSTFGAV 321

  Fly   339 FGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIAGLF----DLSQLVSLL 399
            .|..|...||.|:.|::|.:.:.:..:......|..    |.:||.|:|.|.    :.|..|:||
  Rat   322 NGGFFSGSRVCYAAAREGHMPQLMSMIHVHRLTPAP----ALIFTTAVALLLVIPGNFSTFVNLL 382

  Fly   400 SIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSERFTFGSVCTQLFNVHRV 464
            |..:.|.|......::.||.                  :|.:|..:.:..||..|...|.:::.|
  Rat   383 SFLSWLTYGTTFACLLYLRI------------------KTRNLHHTYKVPTFIPVIMLLVSLYLV 429

  Fly   465 QEPNAISSRIVGVLSTLFCLISLGIGVLIMQAHLLIASKEVWALTLLIVLVV 516
            ..|.....::..:...||.|  .|..|..:..|....||.|...|:.:.|::
  Rat   430 LAPIIDHPQMEFLYIFLFVL--TGFPVYFLLFHFQCQSKCVQTATMHLQLLL 479

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	114/507 (22%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
Slc7a15	NP_001100184.1	2A0308	4..481	CDD:273332	114/507 (22%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351222
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	2	1.930