DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and meu22

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_596348.1	Gene:	meu22 / 2540779	PomBaseID:	SPBC19F8.06c	Length:	574	Species:	Schizosaccharomyces pombe

Alignment Length:	544	Identity:	116/544 - (21%)
Similarity:	192/544 - (35%)	Gaps:	141/544 - (25%)

- Green bases have known domain annotations that are detailed below.

  Fly    23 EGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMISFAIAALASLLAGVCYAEF 87
            |....|.|.|....:..:.:|..:|.|::|.:|....|....|::|:||:.....|......||.
pombe    53 EDTQDLQRKLKPRHMQMIAIGGCVGTGLFVGSGNALADGGPASILIAFAVIGTYVLFTTSALAEL 117

  Fly    88 GARVPKAGSAYVYSYVCIGEFVAFV-IGWNLILEYVIGTASVCRGISLYLDSLLNDTLKYTFAEV 151
            .|..|.:||.|.|       |..|: ..|...:           ||..:|...:...|:.|   |
pombe   118 SAIYPVSGSFYTY-------FSKFIDPAWGFAV-----------GIQYWLSFAVTVPLELT---V 161

  Fly   152 APMNVSF---LGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIF-ILGFVII-----AG 207
            ||:.::|   .|....:::...|::..:.: :|.|.......|::.:.:. ::||||:     ||
pombe   162 APLIINFWNASGPVSIWISVFYVIIIAINI-WGTEGYGEVEFFLSIMKVISVIGFVILSIIIAAG 225

  Fly   208 ALKAD------YSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEEV 266
            .:..|      .|.|. .|..            |..||:|....:....|...|.:.:.....|.
pombe   226 GVPTDDRGVIGVSYWK-QPLV------------FNNGFKGLCAVSVIAIFSLSGTELVGLAASEA 277

  Fly   267 RNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVN---------APLPYAFEYVGWPVA 322
            :||:|.:|.::......|||.|.....:|||::|..:..:.         :|...|.:.......
pombe   278 KNPQKTVPAAVKQIFWRIFLFYIVALFMLTLVVPSDLPGLRTSDNSNVLISPFVIAIQLANIRAL 342

  Fly   323 MWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVS----PRFRVPVT---GSIVAA 380
            ..|:.|..|:..|:....|.:...|.::::|::|...|...|.:    |.:.:.||   |||  |
pombe   343 PSIMNVVILLSTLSVGNSASYAASRALFALAKNGYAPKIFNKTNKRGHPIYAIAVTLLFGSI--A 405

  Fly   381 LFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSS 445
            .||.|..|             |.|..:.:                               |:...
pombe   406 YFTEAGVG-------------GALFGWLL-------------------------------SICGL 426

  Fly   446 SERFTFGSVC---TQLFNVHRVQEPN----------AISSRIVGVLSTLFCLIS------LGIG- 490
            |..|.:||:|   .|.....::|...          .:...|.||..|:..||:      ..||
pombe   427 STTFIWGSICLAHIQFRRAWKIQNRKLEDLPYRSIFGVYGSIYGVAMTILALIAQFYVAVFPIGK 491

  Fly   491 --------VLIMQAHLLIASKEVW 506
                    ...|.|.:||.|...|
pombe   492 KPNPVDFFQAYMAAPILIISFVAW 515

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	116/544 (21%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
meu22	NP_596348.1	LysP	17..544	CDD:223903	116/544 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
TreeFam	0	0.000	Not matched by this tool.
	2	1.900