DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and aat-1

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_501707.1	Gene:	aat-1 / 177793	WormBaseID:	WBGene00000002	Length:	493	Species:	Caenorhabditis elegans

Alignment Length:	449	Identity:	102/449 - (22%)
Similarity:	185/449 - (41%)	Gaps:	94/449 - (20%)

- Green bases have known domain annotations that are detailed below.

  Fly    11 LTRRKNLQADGSEGETK---LNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV---MIS 69
            |..|:..:|..:|.|.|   |.:.|.|::..::.||..:|:|::|....: ::||| ||   :|.
Worm     8 LKSREGDEAPQNETEGKGKGLEKSLTLFNGVSMIVGCIIGSGIFVSPTGV-QEQAG-SVGLSLIV 70

  Fly    70 FAIAALASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVI----GTASVCR 130
            :.|:.:.:.:...||||.|..:.|:|..|.|.....|.||||:..|   :|.::    ....|..
Worm    71 WLISGIFTAIGAYCYAELGTLIKKSGGDYAYIMEAFGPFVAFIRLW---IEAIVVRPCTVTIVAL 132

  Fly   131 GISLYLDSLLNDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCL 195
            ..::|       .|:..|.:.||.:|     ..:.||..|:|:........|..:|:..::.|..
Worm   133 TFAIY-------GLRPFFPDCAPPDV-----VAELLAILLIVLMTAINCISVRLATIVQDWFTIA 185

  Fly   196 NIFILGFVIIAGALKADYSNWTVDPSTVSANSTIGSGGFFPFG-------FEGTLRGAATCF--- 250
            .:..|..:|:.|.                        |...||       ||......:..|
Worm   186 KVVALCLIILTGL------------------------GLLFFGESQYKDSFENIFENTSQDFTKV 226

  Fly   251 --------FGFVGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPY------ 301
                    |.:.|::.:....||::||::|:|.:|.:|:....:.|     |||.:..|
Worm   227 SLAFYSGLFAYSGWNFLNFIVEELQNPKRNLPLAIAISITSCTVIY-----VLTNVALYTAISPD 286

  Fly   302 -YIQDVNAPLPYAFEYVG-----WPVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFK 360
             .::.....:.:|.:..|     .|:.:...|:|       |..|.:|...|:.||.|::|.:..
Worm   287 EMLESPAVAVLFANKLYGKFAFIMPLCVACSTIG-------SANGVIFTSARLFYSGAREGQMPA 344

  Fly   361 FLGKVSPRFRVPVTGSIV-AALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLR 418
            .|..::.:.:.|:...|: .||..|.:....|:.||::.:.|...||......::..||
Worm   345 VLTMINKKTKTPIPAVILTGALSIAYLLASKDVYQLINYIQISYWLAIGTAIAALFWLR 403

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	102/449 (23%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
aat-1	NP_501707.1	2A0308	2..491	CDD:273332	102/449 (23%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910