Protein Alignment CG7255 and Slc7a3

DIOPT Version :9

• Sequence 1: NP_001034016.1
• Gene: CG7255 / 39662
• FlyBaseID: FBgn0036493
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: NP_001288769.1
• Gene: Slc7a3 / 11989
• MGIID: 1100521
• Length: 618
• Species: Mus musculus
• Alignment Length: 651
• Identity: 282/651 - (43%)
• Similarity: 389/651 - (59%)
• Gaps: 77/651 - (11%)

  Fly    11 LTRRKNLQADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMISFAIAAL 75
            |.||:.|:.  ..|||:|.|.|...||.|||||||||||||||||::|||:||||::|.|.:|||
Mouse    13 LVRRRVLEL--GMGETRLARCLSTLDLVALGVGSTLGAGVYVLAGEVAKDKAGPSIVICFLVAAL 75

  Fly    76 ASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYLDSLL 140
            :|:|||:||||||||||.:||||:||||.:||..||..||||||.||||||||.|..|...|:|:
Mouse    76 SSVLAGLCYAEFGARVPGSGSAYLYSYVTVGELWAFTTGWNLILSYVIGTASVARAWSSAFDNLI 140

  Fly   141 ND----TLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILG 201
            .:    |||.|.....|   ..|..|.||.|..||::....|..|...|.:.....|.:|:.:|.
Mouse   141 GNHISRTLKGTILLKMP---HVLAEYPDFFALALVLLLTGLLVLGASKSALVTKVFTGMNLLVLS 202

  Fly   202 FVIIAGALKADYSNW---------TVDPS--TVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVG 255
            ||||:|.:|.:..||         |:..|  |.|.:| :|||||.|||.||.||||||||:.|||
Mouse   203 FVIISGFIKGELRNWKLTKEDYCLTMSESNGTCSLDS-MGSGGFMPFGLEGILRGAATCFYAFVG 266

  Fly   256 FDCIATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVNAPLPYAFEYVGWP 320
            ||||||||||.:||:::||..|::|:.|.||.|||||:.||||:|||.....:|||.||.||||.
Mouse   267 FDCIATTGEEAQNPQRSIPMGIVISMFICFLAYFGVSSALTLMMPYYKLHPESPLPEAFSYVGWE 331

  Fly   321 VAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAA 385
            .|.::|.:|.|..|..||.|::||:||||||||:|||||:.|.||.....:|:..::|:.:..|.
Mouse   332 PARYLVAIGSLCALSTSLLGSMFPMPRVMYSMAEDGLLFRVLAKVHSVTHIPIVATLVSGVIAAF 396

  Fly   386 IAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSL---TSSSE 447
            :|.||:|:.||.|:|||||||:|:|:|.:::|||        .|.|......|...|   |..:|
Mouse   397 MAFLFELTDLVDLMSIGTLLAHSLVSICVLILRY--------QPDQEMKSVEEEMELQEETLEAE 453

  Fly   448 RFTFGSVCTQLFNVHRVQEPNAISSRIV-------GVLSTLFCLISLGIGVLIMQAHLLIASKEV 505
            :.|..::...:.::     |..:|.|:|       .||.|:.||      ||......|.:...|
Mouse   454 KLTVQALFCPVNSI-----PTLLSGRVVYVCSSLLAVLLTVLCL------VLTWWTTPLRSGDPV 507

  Fly   506 WALTLLIVLVVLMLLVICLICLQPREARRRLFRVPFVPIVPAISIFINIYLMLQLDTWTWIRFGV 570
            | :|::::::.|:|.:..:|..||:......|:||.||::|.:|||:|:|||:|:...||.|||:
Mouse   508 W-VTVVVLILGLILAISGVIWRQPQNRTPLHFKVPAVPLLPLVSIFVNVYLMMQMTAGTWARFGI 571

  Fly   571 WMIVGIPVFLACWYLYDCKNPAKRNPERWDFYKALKGLQESREQ--EYHCISKESVLTLETQLKK 633
            ||::|..::..                        .|:|.|.::  .:..:.|....|::..|..
Mouse   572 WMLIGFAIYFG------------------------YGIQHSMKEVKNHQTLPKTRAQTIDLDLTT 612

  Fly   634 S 634
            |
Mouse   613 S 613

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	275/594 (46%)
		AA_permease_C	537..580	CDD:290617	22/42 (52%)
Slc7a3	NP_001288769.1	2A0303	4..588	CDD:273330	277/624 (44%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C167847696
Domainoid	1	1.000	453	1.000	Domainoid score	I498
eggNOG	1	0.900	-	-		E2759_KOG1286
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	1	0.950	-	0	Normalized mean entropy	S2925
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_100168
Panther	1	1.100	-	-	O	PTHR43243
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	11	10.700