DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment CG7255 and Slc7a10

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_446178.2	Gene:	Slc7a10 / 114518	RGDID:	621672	Length:	530	Species:	Rattus norvegicus

Alignment Length:	433	Identity:	105/433 - (24%)
Similarity:	178/433 - (41%)	Gaps:	84/433 - (19%)

- Green bases have known domain annotations that are detailed below.

  Fly    21 GSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV-----MISFAIAALASLLA 80
            |:.....|.:.:||.....:.:|:.:|:|:::....:.:......:     ::...:.||.||
  Rat    35 GASERVALKKEIGLVSACTIIIGNIIGSGIFISPKGVLEHSGSVGLALFVWVLGGGVTALGSL-- 97

  Fly    81 GVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLIL-EYVIGTASVCRGISLYLDSLLNDTL 144
              ||||.|..:||:|..|.|.....|....|::.|:.:| .|....|.:....|.|:       |
  Rat    98 --CYAELGVTIPKSGGDYAYVTEIFGGLAGFLLLWSAVLIMYPTSLAVISMTFSNYV-------L 153

  Fly   145 KYTFAEVAP-------------MNVSFLGSYFDFLAFGLVVVF--GVALAFGVETSTMANNFVTC 194
            :..|....|             |.::::.|.....|..:.|:|  |..||..:
  Rat   154 QPVFPNCIPPATASRVLSMACLMLLTWVNSSSVRWATRIQVIFTGGKLLALSL------------ 206

  Fly   195 LNIFILGFV-IIAGALKA-----DYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGF 253
              |..:||| |..|..:.     .::.| :.||.          |.....|   |:|:    |.|
  Rat   207 --IITVGFVQIFQGHFEELRPTNAFTFW-MTPSV----------GHLALAF---LQGS----FAF 251

  Fly   254 VGFDCIATTGEEVRNPRKNIPKSILLSL-LIIFLCYFGVSTVLTLMLPYYIQDVNAPLPYAFE-- 315
            .|::.:....||:.:||||:|::|.:|: |:.|:..|......|.|.|..:...||......|
  Rat   252 SGWNFLNYVTEELVDPRKNLPRAIFISIPLVTFVYTFTNVAYFTAMSPQELLSSNAVAVTFGEKL 316

  Fly   316 --YVGW--PVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGS 376
              |..|  ||::.:.|.||:.|.       ||...|:.:|.|::|.|..||..:..|...|:...
  Rat   317 LGYFSWVMPVSVALSTFGGINGY-------LFTSSRLCFSGAREGHLPSFLAMIHVRRCTPIPAL 374

  Fly   377 IVAALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRY 419
            :|....||.|..:.|...|::.:|....|.|.|..:.:::||:
  Rat   375 LVCCGATAVIMLVGDTYTLINYVSFINYLCYGVTILGLLVLRW 417

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	105/433 (24%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
Slc7a10	NP_446178.2	2A0308	38..503	CDD:273332	104/430 (24%)
Slc7a10	NP_446178.2	Disordered. /evidence=ECO:0000256\|SAM:MobiDB-lite	508..530
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C166351197
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930