DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and slc7a2.2

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	XP_017948087.1	Gene:	slc7a2.2 / 100494231	XenbaseID:	XB-GENE-5763997	Length:	622	Species:	Xenopus tropicalis

Alignment Length:	643	Identity:	280/643 - (43%)
Similarity:	389/643 - (60%)	Gaps:	64/643 - (9%)

- Green bases have known domain annotations that are detailed below.

  Fly     8 WKVLTRRKNLQADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSVMISFAI 72
            :|:|||.|.:..:| |..:.|.|.|...||.|||||||||||||||||::||..:|||:::||.|
Frog    11 YKILTRTKQVTLEG-ENSSNLCRCLSTLDLVALGVGSTLGAGVYVLAGEVAKVDSGPSIILSFLI 74

  Fly    73 AALASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYLD 137
            |||||:|||:||||||||||..||||:||||.:||..||:.||||||.|||||:||.|..|...|
Frog    75 AALASVLAGLCYAEFGARVPLTGSAYLYSYVTVGELWAFITGWNLILSYVIGTSSVARAWSATFD 139

  Fly   138 SLLNDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAFGVETSTMANNFVTCLNIFILGF 202
            .|:...:....:....|::..|..|.|..|..|:::....|:|||:.||..|...|.:||.:|.|
Frog   140 DLVGKKIGNFLSNTMHMDLPGLAEYPDIFAVCLIILLAGLLSFGVKESTTVNKVFTAINILVLLF 204

  Fly   203 VIIAGALKADYSNWT-------VDPSTVSANS-------TIGSGGFFPFGFEGTLRGAATCFFGF 253
            ||.:|.:..:...|.       |...|||.:|       ..|:|||.||||.|||.||||||:.|
Frog   205 VIASGCVTGNIKYWKMSKEDLWVSKQTVSNHSIGNETGLDFGAGGFMPFGFSGTLAGAATCFYAF 269

  Fly   254 VGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVNAPLPYAFEYVG 318
            |||||||||||||:||:|:||..|:|||.|.|..|||||..||||:||::.|..:|||.||||||
Frog   270 VGFDCIATTGEEVKNPQKSIPLGIVLSLSICFFTYFGVSASLTLMMPYHLLDSQSPLPAAFEYVG 334

  Fly   319 WPVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFT 383
            |.||.:||.||.|..|..||.|::||:||::::||:|||||:.|.::|.| :.||..:||:.:..
Frog   335 WSVAKYIVAVGSLCALTTSLLGSMFPMPRILFAMARDGLLFQPLSRLSSR-QSPVIATIVSGVVA 398

  Fly   384 AAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSER 448
            |.:|.||||..||.::||||||||::|:..::||||....:..::| ...:.....:||:
Frog   399 ALMAFLFDLKALVDMMSIGTLLAYTLVSTCVLLLRYQPQTDFGKSP-DGNLPEQNISSLS----- 457

  Fly   449 FTFGSVCTQLFNVHRVQEPNAISSRIVG----VLSTLFCLISLGIGVLIMQAHLLIASKEVWALT 509
                         |..:.|:..||.:|.    .::.|.|:.|:   |....:..|::.| .|.|:
Frog   458 -------------HPPETPSVHSSALVTHCVLAITLLVCVASV---VSTAGSQCLLSGK-AWCLS 505

  Fly   510 LLIVLVVLMLLVICLICLQPREARRRLFRVPFVPIVPAISIFINIYLMLQLDTWTWIRFGVWMIV 574
            ||::.::.::..:.:|..||:...:..|.|||||::|.:||.:|||||:||.|.||.|:.|||.|
Frog   506 LLVLSLLGIITALVIIWRQPQNQSKATFMVPFVPVLPVVSILVNIYLMVQLSTDTWYRYAVWMAV 570

  Fly   575 GIPVFLACWYLYDCKNPAKRNPERWDFYKALKGLQESREQEYHCISKESVLTLETQLK 632
            |..::..    |..::..:|             ||...:    |..|.::.:.||..|
Frog   571 GFVIYFG----YGIRHSIER-------------LQLMDK----CTQKVAISSTETXCK 607

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	271/589 (46%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617	25/42 (60%)
slc7a2.2	XP_017948087.1	None

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D421901at33208
OrthoFinder	1	1.000	-	-		FOG0000131
OrthoInspector	0	0.000	Not matched by this tool.
Panther	1	1.100	-	-	O	PTHR43243
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X81
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	4	4.110