Protein Alignment CG7255 and slc7a11

DIOPT Version :10

• Sequence 1: NP_001034016.1
• Gene: CG7255 / 39662
• FlyBaseID: FBgn0036493
• Length: 1063
• Species: Drosophila melanogaster
• Sequence 2: XP_009289503.1
• Gene: slc7a11 / 100151597
• ZFINID: ZDB-GENE-150416-1
• Length: 498
• Species: Danio rerio
• Alignment Length: 618
• Identity: 117/618 - (18%)
• Similarity: 222/618 - (35%)
• Gaps: 182/618 - (29%)

  Fly    17 LQADGSEGETKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKD--QAGPSVMISFAIAALASLL 79
            |..:..:.:.:|.:.:.|....::.:|:.:|||:::....|.::  ..|.|:::..|...| ||.
Zfish    28 LNGEPPKEKVELRKKVTLLRGISIIIGTIIGAGIFISPKGILQNSGSVGMSLVVWVACGIL-SLF 91

  Fly    80 AGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGW-NLILEYVIGTASVCRGISLYLDSLLNDT 143
            ..:.|||.|..:.|:|..|.|.....|..||||..| ::|.....|.|.:......|:
Zfish    92 GALSYAELGTCIKKSGGHYTYILEAFGPQVAFVRLWADMIAIRPAGLAVIALAFGRYI------- 149

  Fly   144 LKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVAL-----AFGVETSTMANNFVTCLNIFILGFV 203
                   :.|:   |:......:|..|....|:.:     :..|..:.....|:|...:..:..:
Zfish   150 -------LEPI---FMPCGVPEIAIKLATTIGITIVMYLNSMSVSWTARLQIFLTFSKLLAIAII 204

  Fly   204 IIAG---ALKADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCIATTGEE 265
            |:.|   ..|.:..|:   .:....|:...:|  .|..|...:       :.:.|:..:....||
Zfish   205 IVPGLYQLFKGETKNF---ENAFEVNTAQLTG--LPLAFYSGM-------YAYAGWFYLNFVTEE 257

  Fly   266 VRNPRKNIPKSILLSLLIIFLCYFGVSTVLTLMLPYYIQDVN-------APLPYAFEYVG---WP 320
            |.||.:.:|.:|.:|::|:.:||     .||.:..|.:...:       ..:.:|.:.:|   :.
Zfish   258 VENPERTVPLAICISMVIVMICY-----TLTNVAYYTVMSADELLASNAVAVTFAEKLMGNFSYA 317

  Fly   321 VAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAA 385
            |.:::.     :....|:.|.||.:.|:.:..:::|.|.:.|..:..|...|:...||  |:...
Zfish   318 VPVFVA-----LSCFGSMNGCLFAISRMFFVASREGQLPEVLSMIHIRRHTPLPAVIV--LYPIT 375

  Fly   386 IAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASETTSLTSSSERFT 450
            :..|| |..:.|||:..:.|.:..:.::::.|.|:                           |||
Zfish   376 LLILF-LGDIYSLLNFMSFLRWLFIGVAVVGLIYL---------------------------RFT 412

  Fly   451 FGSVCTQLFNVHRVQEPNAISSRIVGVLSTLFCLISLGIGVLIMQAHLLIASKEVWALTLLIVLV 515
                                                                             
Zfish   413 ----------------------------------------------------------------- 412

  Fly   516 VLMLLVICLICLQPREARRRLFRVP-FVPIVPAISIFINIYLMLQLDTW-TWIRFGVWMIVGIPV 578
                          |....|.|:|| |:|.|.:.:.|..::|.|..|.. |.|.|.: .:.|||.
Zfish   413 --------------RPDLPRPFKVPIFIPAVFSFTCFFMVFLSLYSDPINTGIGFAI-SLTGIPA 462

  Fly   579 FLACWYLYDCKNPAKRNPERWDFYKALKGLQES 611
            :    |::   ..:||.| :| |.|....:..|
Zfish   463 Y----YIF---IHSKRKP-KW-FQKFSDSMNRS 486

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	109/586 (19%)
slc7a11	XP_009289503.1	2A0308	13..497	CDD:273332	117/618 (19%)