DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and slc7a8b

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	XP_001346314.3	Gene:	slc7a8b / 100007990	ZFINID:	ZDB-GENE-030616-586	Length:	501	Species:	Danio rerio

Alignment Length:	524	Identity:	104/524 - (19%)
Similarity:	201/524 - (38%)	Gaps:	96/524 - (18%)

- Green bases have known domain annotations that are detailed below.

  Fly    12 TRRKNLQADGS--EGE--TKLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV-MISFA 71
            |||:......|  :||  ..|.:.:||.....:.||:.:|:|::|....:.::.....: :|.:.
Zfish     6 TRRRTASVPDSDPDGEPAVTLKKEIGLLSACGIVVGNIIGSGIFVSPKGVLENSGSVGLALIVWI 70

  Fly    72 IAALASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILEYVIGTASVCRGISLYL 136
            :..:.:.:..:||||.|..:||:|..|.|.....|....|:..|..:|.......:|
Zfish    71 LTGIITAIGALCYAELGVTIPKSGGDYSYVNDIFGGLAGFLRLWIAVLVIYPTNQAV-------- 127

  Fly   137 DSLLNDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVAL-----AFGVETSTMANNFVTCLN 196
                   :..|||..| :...|...:....|.||:....:.|     ...|..:|...:..|...
Zfish   128 -------IALTFANYA-LQPLFPSCFPPERALGLLAAVCLLLLTWINCSSVRWATRVQDVFTTGK 184

  Fly   197 IFILGFVIIAGALKADYSNWTVDPSTVSANSTIGSGGFF------------PFGFE----GTLRG 245
            :..||.:||.|.::                  |..|.|:            |:...    ..|:|
Zfish   185 LLALGLIIIMGIVQ------------------ICKGHFYWLEPEHAFHPLQPYDMGRIALAVLQG 231

  Fly   246 AATCFFGFVGFDCIATTGEEVRNPRKNIPKSILLSLLIIFLCYFGVS-TVLTLMLPYYIQDVNA- 308
            :    |.:.|::.:....||:.:|.:|:|::|.:|:.::...|...: ..:|.|.|..:...||
Zfish   232 S----FAYAGWNFLNYVTEELIDPYRNLPRAIFISIPLVTFVYVSANIAYVTAMSPQELLASNAV 292

  Fly   309 PLPYAFEYVGWPVAMWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPV 373
            .:.:..:.:|  |..|::.:...:.....:.|:||...|:.::.|::|.|.:.|..:......|:
Zfish   293 AVTFGEKLLG--VMSWLMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPRLLAMIHVNRCTPI 355

  Fly   374 TGSIVAALFTAAIAGLFDLSQLVSLLSIGTLLAYSVVAISIMLLRYMDYCEVDENPGQREVRASE 438
            ...::..:.|..:..:.|:..|::.:.....|.|.|.....::||      :.|....|.::.|.
Zfish   356 PALLITCISTLLMLCVSDIYTLINYVGFINYLFYGVTVAGQIVLR------IREPDIYRPIKVSL 414

  Fly   439 T--------------TSLTSSSERFTFG------SVCTQLFNVHRVQEPNAISSRIVGV--LSTL 481
            .              .||.|.......|      .|...||.::...:|.:.||.:..:  |...
Zfish   415 AWPAVFLIFWAFLLIFSLYSEPVVCCIGLAIMLSGVPVYLFGIYWENKPKSFSSFVARLTHLGQK 479

  Fly   482 FCLI 485
            .||:
Zfish   480 LCLV 483

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	104/524 (20%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
slc7a8b	XP_001346314.3	AA_permease_2	9..488	CDD:330980	101/521 (19%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593030
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930