DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment CG7255 and slc7a8a

DIOPT Version :9

Sequence 1:	NP_001034016.1	Gene:	CG7255 / 39662	FlyBaseID:	FBgn0036493	Length:	1063	Species:	Drosophila melanogaster
Sequence 2:	NP_001258826.1	Gene:	slc7a8a / 100007704	ZFINID:	ZDB-GENE-121120-2	Length:	531	Species:	Danio rerio

Alignment Length:	421	Identity:	89/421 - (21%)
Similarity:	172/421 - (40%)	Gaps:	52/421 - (12%)

- Green bases have known domain annotations that are detailed below.

  Fly    20 DGSEGET--------KLNRVLGLWDLTALGVGSTLGAGVYVLAGQIAKDQAGPSV-MISFAIAAL 75
            ||...:|        .|.:.:||.....:.||:.:|:|::|....:.::.:...: :|.:.:..:
Zfish    19 DGGAADTGNTAGQSVALKKEIGLVSACGIIVGNIIGSGIFVSPKGVLENASSVGLALIVWILTGI 83

  Fly    76 ASLLAGVCYAEFGARVPKAGSAYVYSYVCIGEFVAFVIGWNLILE-YVIGTASVCRGISLYLDSL 139
            .:.:..:||||.|..:||:|..|.|.....|....|:..|..:|. |....|.:....|.|:...
Zfish    84 ITAIGALCYAELGVTIPKSGGDYSYVKDIFGGLAGFLRLWIAVLVIYPTNQAVIALTFSNYVLQP 148

  Fly   140 LNDTLKYTFAEVAPMNVSFLGSYFDFLAFGLVVVFGVALAF-------GVETSTMANNFVTCLNI 197
            |..|.      ..|.|             ||.::..:.|..       .|..:|...:..|...:
Zfish   149 LFPTC------FPPEN-------------GLRILAAICLLLLTWVNCSSVRWATRVQDVFTAGKL 194

  Fly   198 FILGFVIIAGAL---KADYSNWTVDPSTVSANSTIGSGGFFPFGFEGTLRGAATCFFGFVGFDCI 259
            ..|..:||.|.:   |.:|  :.::|:...........|.....|   |:|:    |.:.|::.:
Zfish   195 LALILIIIMGIVQICKGEY--YWLEPANAFEPFQDYDVGLIALAF---LQGS----FAYGGWNFL 250

  Fly   260 ATTGEEVRNPRKNIPKSILLSL-LIIFLCYFGVSTVLTLMLPYYIQDVNA-PLPYAFEYVGWPVA 322
            ....||:.:|..|:|::|.:|: |:.|:..|.....:|.|.|..:...|| .:.:..:.:|  |.
Zfish   251 NYVTEELVDPYVNLPRAIFISIPLVTFVYVFANIAYVTAMSPQELLASNAVAVTFGEKLLG--VM 313

  Fly   323 MWIVTVGGLVGLLASLFGALFPLPRVMYSMAQDGLLFKFLGKVSPRFRVPVTGSIVAALFTAAIA 387
            .||:.:...:.....:.|:||...|:.::.|::|.|...|..:..:...|:...:...:.|..:.
Zfish   314 SWIMPISVALSTFGGVNGSLFTSSRLFFAGAREGHLPSLLAMIHVKRCTPIPALLFTCISTLLML 378

  Fly   388 GLFDLSQLVSLLSIGTLLAYSVVAISIMLLR 418
            ...|:..|::.:.....|.|.|.....::||
Zfish   379 CTSDMYTLINYVGFINYLFYGVTVAGQIVLR 409

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
CG7255	NP_001034016.1	2A0303	9..581	CDD:273330	89/421 (21%)
CG7255	NP_001034016.1	AA_permease_C	537..580	CDD:290617
slc7a8a	NP_001258826.1	2A0308	1..497	CDD:273332	89/421 (21%)
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C170593027
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
ZFIN	0	0.000	Not matched by this tool.
	1	0.930