Protein Alignment Best3 and best-21

DIOPT Version :10

• Sequence 1: NP_730039.1
• Gene: Best3 / 39661
• FlyBaseID: FBgn0036492
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_502846.2
• Gene: best-21 / 190674
• WormBaseID: WBGene00013520
• Length: 395
• Species: Caenorhabditis elegans
• Alignment Length: 436
• Identity: 144/436 - (33%)
• Similarity: 222/436 - (50%)
• Gaps: 54/436 - (12%)

  Fly     1 MTVSYTAEVATCSHFGCFWKLLMRWRASIYKIIWVDLLAFLSCFYFMAVIYRYALRDVDKPVFED 65
            |||:|..||::.:.| .|.||||.||.||:|.:..:|..::..|..:.::|||.:.:..:..||.
 Worm     1 MTVNYNQEVSSVNSF-TFVKLLMTWRGSIWKSVRWELTMWVIAFAVVQMVYRYLMTEDQQKFFEY 64

  Fly    66 IVMYCHSYSNLIPLSFVLGFYVGIIIERWWNQYITVPWPDPLAVYVSALVRGQDEHGRLMRRTIM 130
            ..::.:.....|||:|:|||:|.|:::||.:.:..:.:.:.:|:.|..||.|.|...:::||||:
 Worm    65 SAIHLNVRLIHIPLTFMLGFFVTIVVDRWRSVFTNIGFIENVALSVGTLVAGTDHAAKVLRRTII 129

  Fly   131 RYVCLALTMVLSMISPVIKRRFPTYDQLIEVGLLNANEANIMKAMDVKFPKHPKYWMPIVWAASI 195
            ||:.|:..:||..||..::|||||.:.|:..|.|..:|...|...|..:   .|||:|..||..:
 Worm   130 RYLVLSQVLVLRDISMRVRRRFPTMESLVSGGFLYRDELERMYKCDTMY---NKYWLPTHWANQL 191

  Fly   196 VTRARKEGRIWDDF-SLKSMIDELNKFRAGCNMLIHYDTISVPLVYTQVVTLAVYSYFVASIFGH 259
            |.:|..|.:..|.. |:.|::..:.:||....||..||.:.:|:.|.|||.|||..||:..:...
 Worm   192 VHKAMFETKNVDSVQSMNSVLMNIKEFRQSMEMLTKYDWVPIPIAYPQVVFLAVRVYFIICLVSR 256

  Fly   260 QW-IDRDIKHYNNIVSYYFPLFSTLEFFFFMGWLKVAETLICPFGDDDDDFELNWLIDRNLQVSY 323
            |: :........:||    |:.:.|:|.||:||:||||.|:.|.|:||||||.|||||||:....
 Worm   257 QYLLSAPPTEAQSIV----PIMTILQFVFFVGWMKVAEALLNPLGEDDDDFECNWLIDRNMSTGI 317

  Fly   324 LIVDEMHNDHPQLVRDQ--------YWDEVFPAELPYAVESDRAEHPEASTARLGIPKVVPVTMT 380
            .|||..|:..|.|..|:        ||.                 ||..:.:: ..|..|.::..
 Worm   318 EIVDTCHDSCPPLKLDEPDDESGTMYWC-----------------HPTKNGSQ-APPSAVAISQH 364

  Fly   381 KSEVSLENDFTEFDDEDEYNPEVTIRFARREFSWSKSSVSVSYSYD 426
            |                  ||...:......||...||.|.|:..|
 Worm   365 K------------------NPFTKVLNMVHPFSSGTSSNSSSFRQD 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best3	NP_730039.1	Bestrophin	8..317	CDD:460047	114/310 (37%)
best-21	NP_502846.2	Bestrophin	8..311	CDD:460047	114/310 (37%)