Protein Alignment Best3 and best-7

DIOPT Version :10

• Sequence 1: NP_730039.1
• Gene: Best3 / 39661
• FlyBaseID: FBgn0036492
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_502108.2
• Gene: best-7 / 178030
• WormBaseID: WBGene00007808
• Length: 540
• Species: Caenorhabditis elegans
• Alignment Length: 518
• Identity: 155/518 - (29%)
• Similarity: 277/518 - (53%)
• Gaps: 62/518 - (11%)

  Fly     1 MTVSYTAEVATCSHFGCFWKLLMRWRASIYKIIWVDLLAFLSCFYFMAVIYRYALRDVDKPVFED 65
            ||.:|..::|| |......||:.:|:.|::|.|::||:.:..|:.|::|||||||....:..||.
 Worm     1 MTYNYHYDLAT-SQRKVILKLIFKWKGSLWKAIYLDLIVWCFCYAFISVIYRYALDRSQQDTFER 64

  Fly    66 IVMYCHSYSNLIPLSFVLGFYVGIIIERWWNQYITVPWPDPLAVYVSALVRGQDEHGRLMRRTIM 130
            .:.:|:...:.||::|:|||:|..:|.||..|:..:...|.:|::.|..:.|.||.||::||:|:
 Worm    65 FMQFCNRRLDYIPINFMLGFFVTTVINRWMTQFANLGMIDNIALFTSMYLSGNDERGRILRRSIV 129

  Fly   131 RYVCLALTMVLSMISPVIKRRFPTYDQLIEVGLLNANEANIMKAMDVKFPKHPKYWMPIVWAASI 195
            |...::.|||...|...:::||||.:.::..|::.::|  :.|..:|: .::.|||:...|..::
 Worm   130 RMCVMSQTMVFRDIHIGVRKRFPTLETMVAAGIMTSSE--LKKYNEVE-SRYAKYWLGFNWTFNL 191

  Fly   196 VTRARKEGRIWDDFSLKSMIDELNKFRAGCNMLIHYDTISVPLVYTQVVTLAVYSYFVASIFGHQ 260
            :..||:||||...::..::.:|:..||:|.:::..||.:.:||:|.|:|.:|::.|::..:...|
 Worm   192 LNEARREGRIESAYTQNAIAEEIRTFRSGLSLIWTYDWVPIPLMYPQLVFMAIHCYYLVCLVSRQ 256

  Fly   261 WIDRDIKHYNNIVSYYFPLFSTLEFFFFMGWLKVAETLICPFGDDDDDFELNWLIDRNLQVSYLI 325
            ::..........:....|..:.:||.|:|||||||..|:.|||:|:|||:.|:||||||.|:..|
 Worm   257 FVINSDAVNTTEIDLGVPFMTIIEFIFYMGWLKVAMDLLNPFGEDEDDFDCNFLIDRNLTVAMGI 321

  Fly   326 VDEMHNDHPQLVRDQYW-DEVFPAELPYAVESD-RAEHPEASTARLGIP-KVVPVTM-------- 379
            ||:.|:|.|.|.:|.:| |.|.|.....|.:.: ......|:.|...|| .|..:||
 Worm   322 VDDSHDDGPILEKDMFWNDTVSPLYSSAAAQRNVNFYFGSATNADAQIPDDVRQITMIPHPLNEK 386

  Fly   380 -------------TKSEVSLEND--FTEFDD-----EDEYNPEVTIRFARRE-----FSWSKSSV 419
                         .:|.|.|:.|  |:..::     |.:::.::...|.:|.     |: .:||.
 Worm   387 LDQMYGKRTNRPPVQSVVELKRDQRFSTGNNRKQTLEAKFSNKLGAMFQKRHSKSLTFT-PESST 450

  Fly   420 SVSYSYDNQSIDTLDE-------------KVDEENEGDTRTLDSRNKDDFDRLKEKRDRERVN 469
            ....|.|.:::.|.:.             :||||::...:..:..        |::..|:|||
 Worm   451 KARASTDIETVSTFENTQKPCYSNPDCIVEVDEESQDIPKVTEEP--------KQEPPRKRVN 505

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best3	NP_730039.1	Bestrophin	8..317	CDD:460047	104/308 (34%)
best-7	NP_502108.2	Bestrophin	8..313	CDD:460047	104/308 (34%)