Protein Alignment Best3 and best-26

DIOPT Version :10

• Sequence 1: NP_730039.1
• Gene: Best3 / 39661
• FlyBaseID: FBgn0036492
• Length: 535
• Species: Drosophila melanogaster
• Sequence 2: NP_493478.1
• Gene: best-26 / 173291
• WormBaseID: WBGene00014103
• Length: 411
• Species: Caenorhabditis elegans
• Alignment Length: 386
• Identity: 120/386 - (31%)
• Similarity: 209/386 - (54%)
• Gaps: 43/386 - (11%)

  Fly     1 MTVSYTAEVATCSHFGCFWKLLMRWRASIYKIIWVDLLAFLSCFYFMAVIYRYAL------RDVD 59
            |||.|..:|.|.:....|:|::::.:.:::..|:.:|..||..::...||||..|      |::.
 Worm     1 MTVPYYRDVPTGNALRNFFKIMLKRKGNLFTAIFKELCLFLGLYFLFMVIYRLVLPKSGGQREIR 65

  Fly    60 KPVFEDIVMYCHSYSNLIPLSFVLGFYVGIIIERWWNQYITVPWPDPLAVYVS---ALV------ 115
            | :.|:::.:   ....|||.|:|||:|..:::||....      |.||...|   |:|
 Worm    66 K-IVENLLSH---QEFTIPLEFLLGFFVSSVVDRWRKSL------DSLAYIESCAHAVVIGFPPN 120

  Fly   116 -RGQDEHGRLMRRTIMRYVCLALTMVLSMISPVIKRRFPTYDQLIEVGLLNANEANIMKAMDVKF 179
             .|.|:: .|:||||:||:.::..::...||..::|||.....|.:..|||.||.:.:..::.|
 Worm   121 SNGSDKN-LLIRRTIIRYLVVSQILLYREISLKVRRRFKKLTILGKAKLLNQNEIDKLNKLECK- 183

  Fly   180 PKHPKYWMPIVWAASIVTRARKEGRIWDDFSLKSMIDELNKFRAGCNMLIHYDTISVPLVYTQVV 244
             .:..|::||.||.|::.....:..:.::|::  :..::.:::...::|.:.|.|.:||.|.|.|
 Worm   184 -HYDIYFLPISWALSLIEDKIDKENLANEFTI--LWGQIKEWQTKLSLLRNCDYIPIPLAYPQAV 245

  Fly   245 TLAVYSYFVASIFGHQWIDR-DIKHYNNIVSYYFPLFSTLEFFFFMGWLKVAETLICPFGDDDDD 308
            .|||..||...:|..|.:|| |.|.:..|.  :||:.:|.::.|.|||:||||.|:.|.|:|:||
 Worm   246 FLAVRCYFAVCVFTRQHLDRYDSKMHTWIT--FFPVLTTFQYIFMMGWMKVAEILLNPMGEDEDD 308

  Fly   309 FELNWLIDRNLQVSYLIVDEMHNDHPQLVRDQYWDEVFPAELPY--AVESDRAEH---PEA 364
            ||||::||.||:....||..:..:|.:|...:..::.    .||  ..|.||.::   ||:
 Worm   309 FELNFIIDNNLKNGLDIVSGLCGNHRKLAEHEIENDC----RPYYQTNEQDRKKNRAPPES 365

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best3	NP_730039.1	Bestrophin	8..317	CDD:460047	102/325 (31%)
best-26	NP_493478.1	Bestrophin	15..316	CDD:460047	99/317 (31%)