DRSC - DRSC Integrative Ortholog Prediction Tool

back to: DIOPT - Ortholog Prediction Tool / DIOPT for Diseases and Traits

Protein Alignment Best4 and nr3c1

DIOPT Version :9

Sequence 1:	NP_001097609.1	Gene:	Best4 / 39660	FlyBaseID:	FBgn0036491	Length:	526	Species:	Drosophila melanogaster
Sequence 2:	NP_001016967.1	Gene:	nr3c1 / 549721	XenbaseID:	XB-GENE-484757	Length:	778	Species:	Xenopus tropicalis

Alignment Length:	243	Identity:	43/243 - (17%)
Similarity:	78/243 - (32%)	Gaps:	86/243 - (35%)

- Green bases have known domain annotations that are detailed below.

  Fly   362 PAASTAYMESQSKLQKRHESAMSTLSTRSRNNFRQN------------FLGRPSATGSYSDSIQM 414
            |.::.:...::.:.|...:.|::..||...||..|.            ::|.|...|..:|....
Frog    49 PTSTASQSNTRQQQQFLKQKAVTGDSTNGLNNVPQPDLSKAVSLSMGLYMGEPDTKGMGNDIAFP 113

  Fly   415 EDGPSRVTFSENQF---------------------DLPHD------EANSSHKPSQSTIDFNDLI 452
            ....:.::..|..|                     ::|.|      :.::..:||        ::
Frog   114 PQEQTGISTGETDFSLLEESIASLQATTLPPDRLLEMPEDPGVLKCDVSAQPRPS--------ML 170

  Fly   453 EQRRRERRERIRHRFLDMQSTHLRHD--------TSGA--PY---------TITVLRP-PSDET- 496
            .|........|:....|..:..|..|        |.|.  |:         ..::|.| .:|:|
Frog   171 GQGGSNGNSTIKLSLTDQSTFDLLQDLDIPPDSPTGGKRNPWLDPLFDEEEAFSLLTPLATDDTF 235

  Fly   497 ------LSES----------QEAGDRAQQDPSGSKEPPPN--KTEKQD 526
                  ||||          .:..|||::....:...|..  ||||:|
Frog   236 LMKSEVLSESSKPLGLEDSTHKLSDRAKEGLLSTAALPVTQVKTEKED 283

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Best4	NP_001097609.1	Bestrophin	8..319	CDD:279411
nr3c1	NP_001016967.1	GCR	29..403	CDD:366943	43/243 (18%)
		NR_DBD_GR_PR	420..495	CDD:143546
		NR_LBD_GR	532..778	CDD:132761
Blue background indicates that the domain is not in the aligned region.

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Compara	1	0.930	-	-		C165173179
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.930