Protein Alignment Best4 and best2

DIOPT Version :9

• Sequence 1: NP_001097609.1
• Gene: Best4 / 39660
• FlyBaseID: FBgn0036491
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_988974.1
• Gene: best2 / 394571
• XenbaseID: XB-GENE-991642
• Length: 510
• Species: Xenopus tropicalis
• Alignment Length: 377
• Identity: 176/377 - (46%)
• Similarity: 251/377 - (66%)
• Gaps: 17/377 - (4%)

  Fly     1 MTVTYTSRVSTSSVLSNFLGLLVRWRGSIYKLIWLDLIVFFGLYCLLAITYRLLVNEEGKRFFEA 65
            ||||||:||:.:. ...|..||:.||||||||::.:.:.||.:|..|:|.||..:|||.|.:|:.
 Frog     1 MTVTYTARVANAR-FGGFYKLLLLWRGSIYKLLYKEFLAFFLMYLALSIIYRFFLNEEQKLYFDK 64

  Fly    66 IMSYCEKNGSLIPLSFVLGFFVRIVMNRWWDQYTTIPWPDGIAILISTSIHGSDDRARVMRRTIL 130
            :..||....:|||:||||||:|.:|:||||:||.::|:||.:...||.::||||:..|:.|||::
 Frog    65 VAIYCNNYANLIPVSFVLGFYVNLVVNRWWNQYLSLPFPDRVMCAISGTVHGSDETGRLYRRTLM 129

  Fly   131 RYVCLCQVIVFTMISPRVKRRFPTYTQIIEAGFLLENEKKIIEAMDQAFPSYPKHWMPIVWAASI 195
            ||..|..:::...:|....:||||...::||||:...|:|..|.:..   ||.|:|:|.||..::
 Frog   130 RYCSLSGLLILRSVSTAAFKRFPTIDHVVEAGFMTRLERKKFENLQS---SYNKYWVPCVWFCNL 191

  Fly   196 VMRARRENKIRDDYAVKTIIDELNQLRGNCGFLLYYDWISVPLVYTQVVTVATYSFFLFSVLGQQ 260
            ..:||.|.:||||::.|.:::|||..|||||.|.:|||||||||||||||:|.|||||..::|:|
 Frog   192 ASQARSEGRIRDDHSFKMLMEELNTFRGNCGMLFHYDWISVPLVYTQVVTIAVYSFFLTCLIGRQ 256

  Fly   261 WNESHSDEDGTRIRRWFPILTVLQFFFYMGWLKVAETLINPFGEDDDDFELNWIIDRNLTVSYCI 325
            :.:......|..:..:.|:.|:||||||.|||||||.|||||||||||||:|::||||..||...
 Frog   257 FLDPARGYPGHELDLYVPVFTLLQFFFYAGWLKVAEQLINPFGEDDDDFEINFLIDRNFQVSMLA 321

  Fly   326 VDEMHQEHPELVKDQYWEEVFPNEIPYAQPKMRQNPP-AASTAYMESQSKLQ 376
            ||||:.:.|.:.||:||.        ::.|:    || .|:|.:.:.....|
 Frog   322 VDEMYSDVPPMEKDRYWN--------HSDPR----PPYTAATLFQKHMPSFQ 361

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best4	NP_001097609.1	Bestrophin	8..319	CDD:279411	152/310 (49%)
best2	NP_988974.1	Bestrophin	8..316	CDD:395843	153/311 (49%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	355	1.000	Domainoid score	I987
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	377	1.000	Inparanoid score	I2034
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	1	1.000	-	-		FOG0001515
OrthoInspector	1	1.000	-	-		mtm9346
Panther	1	1.100	-	-	O	PTHR10736
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	8	8.160