Protein Alignment Best4 and best-13

DIOPT Version :9

• Sequence 1: NP_001097609.1
• Gene: Best4 / 39660
• FlyBaseID: FBgn0036491
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_501784.1
• Gene: best-13 / 185198
• WormBaseID: WBGene00009323
• Length: 413
• Species: Caenorhabditis elegans
• Alignment Length: 392
• Identity: 135/392 - (34%)
• Similarity: 219/392 - (55%)
• Gaps: 45/392 - (11%)

  Fly     1 MTVTYTSRVSTSSVLSNFLGLLVRWRGSIYKLIWLDLIVFFGLYCLLAITY----RLLVNEEG-- 59
            ||::|:         .|.:.:|:||:|||::..|.:|:::..||..:.:.|    .|:.::|.
 Worm     1 MTISYS---------GNVIRILLRWKGSIWRTAWKELLIYLILYYSVRVFYLKGIDLIDDDEDDR 56

  Fly    60 ---KRFFEAIMSYCEKNGSLIPLSFVLGFFVRIVMNRWWDQYTTIPWPDGIAILISTSIHGSDDR 121
               :|.||.....|:....||||:|:|||:|..|:.|||.|:.|:.||:.|..::.|.:|..|::
 Worm    57 LKMRRMFETFCRQCDSYTRLIPLTFLLGFYVSNVVARWWRQFETLYWPEDILSVLCTVLHQHDEK 121

  Fly   122 ARVMRRTILRYVCLCQVIVFTMISPRVKRRFPTYTQIIEAGFLLENEKKIIEAMDQAFPSYPKHW 186
            ::..|.||.||:.|...:.:..||.:::.|||:...:||:|.|.|.|.:|:|||.....|  ..|
 Worm   122 SKRRRHTIARYLNLANALAWRDISSKIRLRFPSVHSLIESGLLTEKEYQILEAMHAENES--SRW 184

  Fly   187 M-PIVWAASIVMRARRENKIRDDYAVKTIIDELNQLRGNCGFLLYYDWISVPLVYTQVVTVATYS 250
            : |:.|...|:.:...|:|.... .....:.||...|.:...|..|||:.||||||||..:||||
 Worm   185 ITPLHWIQLIMRQVEEEHKPTAS-LFNQFVGELRIFRQSLRKLYSYDWVCVPLVYTQVAALATYS 248

  Fly   251 FFLFSVLGQQWNESHSD-EDGTRIRRWFPILTVLQFFFYMGWLKVAETLINPFGEDDDDFELNWI 314
            ||.|::.|:|  ....| |.|..:....|:.|::||.|::||.||.:.|:.|||.||||.|||:|
 Worm   249 FFFFTLFGRQ--PLFPDIETGKELDLVVPVFTIVQFLFFVGWFKVGQDLMRPFGLDDDDIELNYI 311

  Fly   315 IDRNLTVSYCIVDEMHQEHP----ELVKDQYWEEVFP-------------NEIPYAQ--PKMRQN 360
            :|||:.:|:.||::: ||.|    |...|:.|.|:.|             .::|:::  .::.::
 Worm   312 LDRNVRISFAIVNQL-QESPIPDFESNDDKLWHEMHPPTKDGETSPIPRIPQLPHSKYSKQLSEH 375

  Fly   361 PP 362
            ||
 Worm   376 PP 377

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best4	NP_001097609.1	Bestrophin	8..319	CDD:279411	117/321 (36%)
best-13	NP_501784.1	Bestrophin	7..316	CDD:279411	117/313 (37%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28981
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	5	4.830