Protein Alignment Best4 and best-9

DIOPT Version :9

• Sequence 1: NP_001097609.1
• Gene: Best4 / 39660
• FlyBaseID: FBgn0036491
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_001379597.1
• Gene: best-9 / 183419
• WormBaseID: WBGene00016613
• Length: 399
• Species: Caenorhabditis elegans
• Alignment Length: 424
• Identity: 129/424 - (30%)
• Similarity: 227/424 - (53%)
• Gaps: 58/424 - (13%)

  Fly     1 MTVTYTSRVSTSSVLSNFLGLLVRWRGSIYKLIWLDLIVFFGLYCLLAIT------YRLLVNEEG 59
            ||::|:         .||..||:||:|||::.:|.:|.:|..|:..:..:      |....:.:|
 Worm     1 MTISYS---------GNFFRLLLRWKGSIWRSVWRELFLFLFLFYFIRFSAPHFFNYTDPTDSKG 56

  Fly    60 -KRFFEAIMSYCEKNGSLIPLSFVLGFFVRIVMNRWWDQYTTIPWPDGIAILISTSIHGSDDRAR 123
             ::.|:.:.:...:...:|||:|:|||:|..|::|||.|:.|:.||:....::...:...:  :|
 Worm    57 YRKIFKVMCNEFHEYTKMIPLTFLLGFYVSNVVSRWWRQFETLRWPEDFLSILCLLLPSKE--SR 119

  Fly   124 VMRRTILRYVCLCQVIVFTMISPRVKRRFPTYTQIIEAGFLLENEKKIIEAMDQAFPSY----PK 184
            ..|..|.||:.|...:.:..:|.:::.|||:...||:||.|.|.|.:.::.:::..|..    |.
 Worm   120 PARHQIARYLNLTSALAWRDVSTKIRLRFPSLRNIIDAGLLTEKEYEKLQDINEPSPGIRWLTPL 184

  Fly   185 HWMPIVWAASIVMRARRENKIRDDYAVKTIIDELNQLRGNCGFLLYYDWISVPLVYTQVVTVATY 249
            ||:..:..|.|.......|.:    :|.|  :||...|.:...|..:||:.||||||||..:|||
 Worm   185 HWVQQLIDAEITAGRGSVNYV----SVAT--NELKAYRISFRRLYCHDWVCVPLVYTQVAALATY 243

  Fly   250 SFFLFSVLGQQWNESHSDEDGTRIRRWFPILTVLQFFFYMGWLKVAETLINPFGEDDDDFELNWI 314
            |:|.|.:.|:| :.:|  :|...:..:||:.||:||.|::||.||.:.|:.|||.|||||||::|
 Worm   244 SYFFFCLFGRQ-DLNH--DDFYSLDAFFPLFTVVQFLFFVGWFKVGQDLMRPFGLDDDDFELSYI 305

  Fly   315 IDRNLTVSYCIVDEMHQEH-PELVKDQYW----------EEVF----PNEIPYAQPKMRQN---- 360
            :|||:..|:.|||.:..:. |:..:|.:|          :.:|    |..:.:.:..:.:|
 Worm   306 LDRNIVTSFTIVDSLQDDDPPKFEEDVFWKHHNEQQQMHQSMFLPRVPTSLKWGRIDLSRNAHKH 370

  Fly   361 PPAASTAYMESQSKLQKRHESAMSTLSTRSRNNF 394
            ||...| |:|.:::..:.:::       |..|.|
 Worm   371 PPKLHT-YLEMKNQDPEEYKN-------RKNNKF 396

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best4	NP_001097609.1	Bestrophin	8..319	CDD:279411	107/321 (33%)
best-9	NP_001379597.1	Bestrophin	4..310	CDD:395843	108/325 (33%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
Isobase	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	3	2.820