Protein Alignment Best4 and best-2

DIOPT Version :9

• Sequence 1: NP_001097609.1
• Gene: Best4 / 39660
• FlyBaseID: FBgn0036491
• Length: 526
• Species: Drosophila melanogaster
• Sequence 2: NP_502524.2
• Gene: best-2 / 182044
• WormBaseID: WBGene00007204
• Length: 421
• Species: Caenorhabditis elegans
• Alignment Length: 445
• Identity: 154/445 - (34%)
• Similarity: 241/445 - (54%)
• Gaps: 66/445 - (14%)

  Fly     1 MTVTYTSRVSTSSVLSNFLGLLVRWRGSIYKLIWLDLIVFFGLYCLLAITYRLLVNEEGKRFFEA 65
            ||:.|...:.||.....|: ||.||:|||:|.|:::.|:|...|.::::.||..::|..:|.||:
 Worm     1 MTINYHKEIKTSHTWKFFV-LLFRWKGSIWKAIYMETIIFLICYGIISVVYRTAMSEPSQRTFES 64

  Fly    66 IMSYCEKNGSLIPLSFVLGFFVRIVMNRWWDQYTTIPWPDGIAILISTSIHGSDDRARVMRRTIL 130
            ::.||:|..|.|||.|||||||.||::||...:.|:.:.|.:.:|.:..:.|:.::|.:.||.|.
 Worm    65 VIRYCDKRLSFIPLEFVLGFFVTIVVDRWTKLWRTVGFIDDVCLLANLYVRGTSEKAIIYRRNIA 129

  Fly   131 RYVCLCQVIVFTMISPRVKRRFPTYTQIIEAGFLLENEKKIIEAMDQAFPSY---------PKHW 186
            ||..|.|::||..:|.|.:|||||...::.|||:.::|..:       :.||         .|:|
 Worm   130 RYCALTQLLVFRDVSMRTRRRFPTMETVVAAGFMSKDELDL-------YNSYTTKNNSRLGKKYW 187

  Fly   187 MPIVWAASIVMRARRENKIRDDYAVKTIIDELNQLRGNCGFLLYYDWISVPLVYTQVVTVATYSF 251
            :|..||..:..:||::..|..||....:..|:...|.|..::..|||:.:||:|.|:|.:|...:
 Worm   188 IPANWALCMTYKARKDGYIESDYFKAQMEGEIRTWRTNIEWVCNYDWVPLPLMYPQLVCLAVNLY 252

  Fly   252 FLFSVLGQQW-NESHSDEDGTRIRRWFPILTVLQFFFYMGWLKVAETLINPFGEDDDDFELNWII 315
            ||.|::.:|. .|.|...|...:  :||::|.|||.||||||||.|.::|||||||||||.|.:|
 Worm   253 FLVSIIARQLVIEKHKMVDEVDV--YFPVMTFLQFIFYMGWLKVIEVMLNPFGEDDDDFETNALI 315

  Fly   316 DRNLTVSYCIVDEMHQEHPELVKDQYWEEVFPNEIPYAQPKMRQNPPAASTAYMESQSKLQKRHE 380
            |||:|:...:||.. .:.|||:|||:::||.                 .|..|.|..|::...|.
 Worm   316 DRNITMGLKMVDNT-MKTPELLKDQFFDEVL-----------------VSLLYSEESSQISNYHY 362

  Fly   381 SAMSTLSTRSRNNFRQNFLGRPSATGSYSDSIQMEDGPSRVTF---SENQFDLPH 432
            .                        ||.|: :.:|...|.|..   |::::.|.|
 Worm   363 H------------------------GSTSE-VHLEQKCSSVRMIPHSQSEYTLKH 392

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Best4	NP_001097609.1	Bestrophin	8..319	CDD:279411	125/320 (39%)
best-2	NP_502524.2	Bestrophin	8..319	CDD:279411	125/320 (39%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	282	1.000	Domainoid score	I871
eggNOG	1	0.900	-	-		E1_KOG3547
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	299	1.000	Inparanoid score	I1638
Isobase	0	0.000	Not matched by this tool.
OMA	1	1.010	-	-		QHG28981
OrthoDB	1	1.010	-	-		D145964at33208
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	1	0.900	-	-		OOG6_101870
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X320
SwiftOrtho	1	1.000	-	-
TreeFam	0	0.000	Not matched by this tool.
	9	8.780