Protein Alignment Tak1 and ripk1

DIOPT Version :9

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001072503.1
• Gene: ripk1 / 779958
• XenbaseID: XB-GENE-1012365
• Length: 669
• Species: Xenopus tropicalis
• Alignment Length: 681
• Identity: 156/681 - (22%)
• Similarity: 270/681 - (39%)
• Gaps: 142/681 - (20%)

  Fly     8 ALQAAYVDFSEITLREKVGHGSYGVVCKAVWR-DKLVAVKEFF-----ASAEQKDIEKEVKQLSR 66
            :|:...:...::..:.|:..|..|:|.....| ..||.:|..:     ..:.:|.:| |.|.:..
 Frog     6 SLENIIMKSEDLINQHKLDAGGCGLVSLCHHRIHGLVVLKTVYTGYMHTQSNEKLLE-EGKIMHM 69

  Fly    67 VKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAM 131
            :|:..::.|.|:....:...|:||:...|.|...|.....|   |:....:..:..||::|||
 Frog    70 LKNDRVVKLLGLILENENYSLVMEYIRNGHLLTVLQQVEVP---LSVKTRFILEIIEGMSYLH-- 129

  Fly   132 TPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVA---------DKSTMM-----------TNNRGS 176
             .:.::|:|:||.|:|: ::..::||.|.|...         ::|.:.           .:|.|:
 Frog   130 -DQKVVHKDLKPENILV-DEDFHIKIADLGLATFNRWSKLTKEQSKLQRKYMHQSTGSYKSNAGT 192

  Fly   177 AAWMAPEVFE--GSKYTEKCDIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERP---PLLT 236
            ..:||||...  .::.|||.|::|:.||.|.:.:.|:|::...|...|.:.:.|.|||   .|..
 Frog   193 LIYMAPEHLRSLNARPTEKSDVYSFGIVTWVIFTNKEPYENALNDEQISYCVKKSERPCLEELPE 257

  Fly   237 TCPKRIEDLMTACWKTVPEDRPSMQ---------YIVGVMHEIVKDYTGADKALEYTFVNQQIVT 292
            .||....|||..||...|:.||..:         |.:..|..:.||   .|| ::..|....::.
 Frog   258 ECPPEALDLMQQCWDDNPDKRPLFKECDCQFRPFYTLKQMMHVEKD---VDK-MKSEFERPNVIV 318

  Fly   293 KESDG---TVAAQPDSLSSQEGELSPSSTQLTPTTAANANVNAIAISKTTTSSMTENTSSTSSDI 354
            :....   ...|:|.||..::..||..|:|...||      |.:..| ....::.|...|.....
 Frog   319 ERMASLQLDCVAEPPSLQPRDQPLSLHSSQGFITT------NQVDES-LFGPALNEPIESEDPRQ 376

  Fly   355 TPTNSGQLDNNPLFYMVTNRWDAIPEEESNESRNDSFNLTSSAEATQRLETIRNGMILMACKPME 419
            ..|...:|.|...::...:|.|.|..:        |:...||.|  :|.:.:.|
 Frog   377 DETLERKLQNEINYHQNGSRLDNIGSQ--------SYTPKSSLE--ERSKKVFN----------- 420

  Fly   420 QLTLDVEANGFDLSPSESSSSSTNAKSDGRERLTVTDTKPVMMTTDLSN----------NNGGIH 474
                  ||:|.:..|  ::|..||:...|...      .|....:..:|          |.|.:.
 Frog   421 ------EASGMNHIP--AASGFTNSPIAGNFE------TPFYPASHFNNWQDIYQRPDQNRGYVP 471

  Fly   475 AHSNG---LLSHAN-GWQARD---EELQEQEHEQE-----------IVNSLDVDVDPDEDENDGT 521
            ..|.|   |..::| .|:.::   |...:..|.:.           :.|.|:|.:........|.
 Frog   472 VGSYGQTSLSQNSNTDWKEKNPTPETGAQSSHPRSQLFARDDRTGVVDNGLNVSISNSNSIQIGN 536

  Fly   522 EQSLAEILD-PELQPE--PPIPNDA-------ESQLIYRD-HRHMAKEYLSVDTNLYYAQ-DFKD 574
            ..:|:.|.: |:.:||  ....|.:       |.|.|..| |..:.:|.||....|:... .|::
 Frog   537 HNTLSVISNRPKPRPEYITRTSNSSVEDLAAFECQTIVNDNHLQLLRENLSKKWKLFARHLGFRE 601

  Fly   575 KLIVQMDRT-EREQKQE----LLRKMKDKEG 600
            ..|.::|.. ||:..||    .|.|.|.:||
 Frog   602 PEIDEIDHDYERDGLQEKVHQTLHKWKMREG 632

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	73/284 (26%)
		STKc_TAK1	25..275	CDD:270960	75/289 (26%)
ripk1	NP_001072503.1	PKc_like	23..293	CDD:328722	71/277 (26%)
		DD	576..660	CDD:326335	18/57 (32%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910