Protein Alignment Tak1 and ripk4

DIOPT Version :9

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_002941332.1
• Gene: ripk4 / 733737
• XenbaseID: XB-GENE-494474
• Length: 717
• Species: Xenopus tropicalis
• Alignment Length: 559
• Identity: 135/559 - (24%)
• Similarity: 225/559 - (40%)
• Gaps: 145/559 - (25%)

  Fly    23 EKVGHGSYGVVCKAVWRDKLVAVKEFFA----------SAEQKDIEKEVKQLSRVKHPNIIALHG 77
            ||||.|.:|.|.|.    |.::.|.:.|          ..|:.::.:|.|::...|...|:.::|
 Frog    26 EKVGSGGFGQVYKV----KHISWKTWLAIKCPPSLHVDEKERIELVEEAKKMEMAKFRCILPVYG 86

  Fly    78 ISSYQQATYLIMEFAEGGSLHNFLHGKVKP---AYSLAHAMSWARQCAEGLAYLHAMTPKPLIHR 139
            |.|  ....|:||:.|.|||...|..:..|   .:.:.|      :.|.|:.:||.|.| ||:|.
 Frog    87 ICS--DPVGLVMEYMETGSLEKLLASECLPWDLRFRIIH------ETAVGMNFLHCMNP-PLLHL 142

  Fly   140 DVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNR--------GSAAWMAPEVF--EGSKYTEKC 194
            |:||.|:||... .::||.|||..  |...::|:.        |:.|::.||.|  :...:..|.
 Frog   143 DLKPANILLDGH-YHVKISDFGLA--KWNGLSNSHELSLDGICGTIAYLPPERFKEKNRSFDTKH 204

  Fly   195 DIFSWAIVLWEVLSRKQPFKGIDNAYTIQWKIYKGERPPLL-------TTCPKRIEDLMTACWKT 252
            |::|:|||:|.:|::::||....|...|..|:..|.||.|.       ..|...|: ||..||..
 Frog   205 DVYSFAIVIWGILAQRKPFAEEKNILHIMVKVGGGLRPDLSQIPRVRPQQCQGMIQ-LMKECWHD 268

  Fly   253 VPEDRPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESD-------------GTVAAQPD 304
            .|:.||:.|                    |.|...:.:.||..|             ||:.|:.:
 Frog   269 KPDKRPTFQ--------------------EITSETEHLCTKHEDETSCVQAQELHGKGTLDAEAE 313

  Fly   305 SLSSQEGELSPSSTQLTPTTAANANVNAIAISKTTTSSMTENTSSTSSDITPTNSG-----QLDN 364
            ::.||      :..:.:||.|.:.:.           |::|..|...|.|:.|..|     ...:
 Frog   314 NVGSQ------AECKRSPTPAFDKDY-----------SLSELLSQLDSGISQTMEGPGCLSHSVS 361

  Fly   365 NPLFYMVTNRWDAIPEEESNESRNDSFNLT---------SSAEATQR---LETIRNGMILMACKP 417
            .|.......|...:...:|..|...|.:|:         .||...|:   ::.|..|......|.
 Frog   362 EPQLASSDKRLSGVSSVDSAFSSRGSLSLSFEKDCSVLDISANDIQKKKLIDAIAGGDTAKLMKI 426

  Fly   418 MEQLTLDVEANGFDLSPSESSSSSTNAKSDGRER----LTVTDTKPVMMTTDLSNNNGGIHAHSN 478
            ::...:|:...|       .||....|..:|:|.    |.:.:..|     :::|..|....|.
 Frog   427 LQPQDVDLVLEG-------RSSLLHLAVENGQEECAKLLLLYNASP-----NMTNLKGSTPLHI- 478

  Fly   479 GLLSHANGWQARDEELQEQEHEQEIVNSLDVDVD-PDED 516
                      |.|::|   ::..|::....::|: .|||
 Frog   479 ----------AADKKL---KNIVELLLGKKINVNAKDED 504

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	83/270 (31%)
		STKc_TAK1	25..275	CDD:270960	81/279 (29%)
ripk4	XP_002941332.1	STKc_RIP4_like	25..291	CDD:270927	87/301 (29%)
		PHA03095	440..>703	CDD:222980	18/84 (21%)
		ANK repeat	441..469	CDD:293786	6/32 (19%)
		ANK repeat	471..502	CDD:293786	7/44 (16%)
		ANK repeat	504..535	CDD:293786	1/1 (100%)
		ANK repeat	538..568	CDD:293786
		ANK repeat	570..602	CDD:293786
		ANK repeat	604..633	CDD:293786
		ANK repeat	637..668	CDD:293786
		ANK repeat	670..701	CDD:293786

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoDB	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	1	0.910