Protein Alignment Tak1 and map3k7

DIOPT Version :9

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: XP_009292938.1
• Gene: map3k7 / 553788
• ZFINID: ZDB-GENE-041001-135
• Length: 578
• Species: Danio rerio
• Alignment Length: 661
• Identity: 223/661 - (33%)
• Similarity: 328/661 - (49%)
• Gaps: 148/661 - (22%)

  Fly     1 MATASLDALQA------AYVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVKEFFASAEQKDIEK 59
            |:..|.|.|:.      ..:|:.:|.:.|.||.|::||||||.|:.:.||:|...:.:|:.....
Zfish     1 MSMPSADMLETPPMYPFEEIDYVDIEVEEVVGRGAFGVVCKAKWKGRDVAIKTIESESEKNAFIV 65

  Fly    60 EVKQLSRVKHPNIIALHGISSYQQATYLIMEFAEGGSLHNFLHG-KVKPAYSLAHAMSWARQCAE 123
            |::|||||.||||:.|:|  |......|:||:||||||:|.||| :..|.|:.:|||||..||::
Zfish    66 ELRQLSRVDHPNIVKLYG--SCNNPVCLVMEYAEGGSLYNVLHGAEPLPHYTASHAMSWCLQCSQ 128

  Fly   124 GLAYLHAMTPKPLIHRDVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRGSAAWMAPEVFEGS 188
            |::|||.|.||.|||||:||.||||...|..||||||||..|..|.||||:||||||||||||||
Zfish   129 GVSYLHGMKPKALIHRDLKPPNLLLVAGGTVLKICDFGTACDIQTHMTNNKGSAAWMAPEVFEGS 193

  Fly   189 KYTEKCDIFSWAIVLWEVLSRKQPFKGIDN-AYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKT 252
            .|:||||:|||.|:||||::|::||..|.. |:.|.|.:::|.||||:...||.||.|||.||..
Zfish   194 NYSEKCDVFSWGIILWEVITRRKPFDEIGGPAFRIMWAVHRGTRPPLIKNLPKAIESLMTRCWSK 258

  Fly   253 VPEDRPSMQYIVGVMHEIVKDYTGADKALEYTFVNQQIVTKESDGTVAAQPDSLSSQEGELSPSS 317
            .|..||||:.||.:|..::..:.|:::.|:|.:       :.||          ..|....:.:.
Zfish   259 DPSQRPSMEEIVKIMSHLMGYFPGSEEPLKYPY-------QYSD----------EGQSNSATSTG 306

  Fly   318 TQLTPTTAANAN-VNAIAISKTTTSSMTENTSSTSSDIT------PTN-SGQ-LDNNPLFYMVTN 373
            :.|..|..:|.| :|            .|:|:|..|:.|      |.. ||| |........:..
Zfish   307 SHLDYTCTSNKNDIN------------MEHTNSPGSNDTIKFPYKPKGISGQSLSRGSSVESLPG 359

  Fly   374 RWDAIPEEESNESRNDSFNLTSSAEATQRL---------------ETIRNGMIL--------MAC 415
            |....|   |::|:..|..|   :|...||               :|..:|.||        ..|
Zfish   360 RSHFQP---SSDSKRMSVEL---SELEPRLPFASPARPQYKRGHRKTASHGTILDIPKIIVTATC 418

  Fly   416 KPMEQLTL-DVEANGFDLSPSESSSSSTNAKSDGRERLTVTDTKPVMMTTDLSNNNGGIHAHSNG 479
            :|..:.:: |:.|.|.|.|....::|.:::.|             ..|.|
Zfish   419 EPHRRRSVQDLPAIGTDASQDSRNNSRSSSPS-------------FRMIT--------------- 455

  Fly   480 LLSHANGWQARDEELQEQEHEQEIVNSLDVDVDPDEDENDGTEQSLAE---ILDPELQPEPPIPN 541
                                             ||..:.:|::.|:..   .||.:|||..|.||
Zfish   456 ---------------------------------PDRTDTNGSDNSIPMAYLTLDHQLQPLAPCPN 487

  Fly   542 DAESQLIYRDHRHMAKEYLSVDTNLYYAQDFKDKLIVQMDRTEREQK------QELLRKMKDKEG 600
            ..||..::..|..||:|||.|.|.:...:..|::||.::|:.|::|:      ||..:.:::.:.
Zfish   488 SKESMAVFEQHCKMAQEYLKVQTEIALLKQRKEELIAELDQDEKDQQNACRLAQEQKKLIEENKS 552

  Fly   601 LQSLYNNLQQQ 611
            |.:.|...::|
Zfish   553 LSTYYQQCKKQ 563

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	137/246 (56%)
		STKc_TAK1	25..275	CDD:270960	138/251 (55%)
map3k7	XP_009292938.1	TyrKc	25..273	CDD:197581	139/249 (56%)
		STKc_TAK1	31..281	CDD:270960	138/251 (55%)

Information from Original Tools

Tool	Simple Score	Weighted Score	Original Tool Information
			BLAST Result	Score	Score Type	Cluster ID
Compara	0	0.000	Not matched by this tool.
Domainoid	1	1.000	288	1.000	Domainoid score	I1543
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	1	1.000	-	-
Homologene	0	0.000	Not matched by this tool.
Inparanoid	1	1.050	368	1.000	Inparanoid score	I2099
OMA	0	0.000	Not matched by this tool.
OrthoDB	1	1.010	-	-		D346131at33208
OrthoFinder	1	1.000	-	-		FOG0000676
OrthoInspector	1	1.000	-	-		oto39755
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	1	0.910	-	-
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	1	1.000	-	-		X4191
SwiftOrtho	0	0.000	Not matched by this tool.
TreeFam	1	0.960	-	-
ZFIN	0	0.000	Not matched by this tool.
	9	8.930