DRSC - DRSC Integrative Ortholog Prediction Tool

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Protein Alignment Tak1 and ark1

DIOPT Version :9

Sequence 1:	NP_524080.1	Gene:	Tak1 / 39659	FlyBaseID:	FBgn0026323	Length:	678	Species:	Drosophila melanogaster
Sequence 2:	NP_001018849.1	Gene:	ark1 / 3361036	PomBaseID:	SPCC320.13c	Length:	355	Species:	Schizosaccharomyces pombe

Alignment Length:	250	Identity:	77/250 - (30%)
Similarity:	130/250 - (52%)	Gaps:	19/250 - (7%)

- Green bases have known domain annotations that are detailed below.

  Fly    25 VGHGSYGVVCKAVWRDK----LVAVK-----EFFASAEQKDIEKEVKQLSRVKHPNIIALHGISS 80
            :|.|.:|.|..|  ::|    :||:|     |...|..:|.:.:|::..|.::|.||:.|:|...
pombe    95 LGKGKFGRVYLA--KEKKTGFIVALKTLHKSELVQSKIEKQVRREIEIQSNLRHKNILRLYGHFH 157

  Fly    81 YQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHRDVKPLN 145
            .::..|||:|||..|.|:.  |.:....:|...|..:..|.|..|:|||   .|.:||||:||.|
pombe   158 DEKRIYLILEFAGRGELYQ--HLRRAKRFSEEVASKYIFQMANALSYLH---KKHVIHRDIKPEN 217

  Fly   146 LLLTNKGRNLKICDFG-TVADKSTMMTNNRGSAAWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSR 209
            :||...| .:|:.||| :|...|...|...|:..::.||:.||.::|||.|::|..::.:|.|..
pombe   218 ILLGIDG-EIKLSDFGWSVHAPSNRRTTLCGTLDYLPPEMVEGKEHTEKVDLWSLGVLTYEFLVG 281

  Fly   210 KQPFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIV 264
            ..||:.:........:|.|.:. .:.:..|....||::...:..||.|.|::.::
pombe   282 APPFEDMSGHSATYKRIAKVDL-KIPSFVPPDARDLISRLLQHNPEKRMSLEQVM 335

Known Domains:

Indicated by green bases in alignment.

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	TyrKc	19..264	CDD:197581	77/248 (31%)
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	77/249 (31%)
ark1	NP_001018849.1	STKc_Aurora	89..341	CDD:270909	77/249 (31%)
ark1	NP_001018849.1	S_TKc	89..340	CDD:214567	77/249 (31%)

Information from Original Tools:

Tool	Simple Score	Weighted Score	Original Tool Information
Tool	Simple Score	Weighted Score	BLAST Result	Score	Score Type	Cluster ID
Domainoid	0	0.000	Not matched by this tool.
eggNOG	0	0.000	Not matched by this tool.
Hieranoid	0	0.000	Not matched by this tool.
Homologene	0	0.000	Not matched by this tool.
Inparanoid	0	0.000	Not matched by this tool.
OMA	0	0.000	Not matched by this tool.
OrthoFinder	0	0.000	Not matched by this tool.
OrthoInspector	0	0.000	Not matched by this tool.
orthoMCL	0	0.000	Not matched by this tool.
Panther	0	0.000	Not matched by this tool.
Phylome	0	0.000	Not matched by this tool.
RoundUp	0	0.000	Not matched by this tool.
SonicParanoid	0	0.000	Not matched by this tool.
TreeFam	0	0.000	Not matched by this tool.
	0	0.000