Protein Alignment Tak1 and Map3k21

DIOPT Version :10

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001418265.1
• Gene: Map3k21 / 307950
• RGDID: 1306091
• Length: 996
• Species: Rattus norvegicus
• Alignment Length: 363
• Identity: 111/363 - (30%)
• Similarity: 176/363 - (48%)
• Gaps: 86/363 - (23%)

  Fly    13 YVDFSEITLREKVGHGSYGVVCKAVWRDKLVAVK------EFFASAEQKDIEKEVKQLSRVKHPN 71
            :|||..:.|:|.:|.|.:|.|.:|.|:.:.||||      |..|:|..:.:.:|.:..:.::|||
  Rat   104 HVDFERLELKELIGAGGFGQVYRATWQGQEVAVKAARRDPEQDAAAAAESVRREARLFAMLRHPN 168

  Fly    72 IIALHGISSYQQATYLIMEFAEGGSLHNFLHG--------------KVKPAYSLAHAM-SWARQC 121
            ||.|.|:...|....|::|||.||:|:..|..              ::.|     |.: :||.|.
  Rat   169 IIQLRGVCLQQPHLCLVLEFARGGALNRALAAAAPDPRVPGPRRARRIPP-----HVLVNWAVQI 228

  Fly   122 AEGLAYLHAMTPKPLIHRDVKPLNLLLTNK-------GRNLKICDFGTVAD--KSTMMTNNRGSA 177
            |.|:.|||.....|::|||:|..|:||..|       .:.|||.|||...:  ::|.| :..|:.
  Rat   229 ARGMLYLHEEAVVPILHRDLKSSNILLLEKIEHDDICNKTLKITDFGLAREWHRTTRM-SAAGTY 292

  Fly   178 AWMAPEVFEGSKYTEKCDIFSWAIVLWEVLSRKQPFKGID----------NAYTIQWKIYKGERP 232
            |||||||...|.:::..||:|:.::|||:|:.:.|::|||          |..|:
  Rat   293 AWMAPEVIRSSLFSKGSDIWSYGVLLWELLTGEVPYRGIDGLAVAYGVAVNKLTL---------- 347

  Fly   233 PLLTTCPKRIEDLMTACWKTVPEDRPSMQYIVGVM----------------HEIVKDYTGADKAL 281
            |:.:|||:....||..||:..|..|||...|:..:                |.:.:|:     .|
  Rat   348 PIPSTCPEPFAKLMKECWEQDPHIRPSFALILKQLTAIEEAVLTDLPQESFHSMQEDW-----KL 407

  Fly   282 EYTFVNQQIVTKESDGTVAAQPDSLSSQEGELSPSSTQ 319
            |...:..::.|||.:         |.|:|.|||.::.|
  Rat   408 EIQQMFSELRTKEKE---------LRSREEELSRAALQ 436

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	94/305 (31%)
Map3k21	NP_001418265.1	SH3	28..84	CDD:473055
		STKc_MLK4	115..385	CDD:271048	92/285 (32%)