Protein Alignment Tak1 and Fer

DIOPT Version :10

• Sequence 1: NP_524080.1
• Gene: Tak1 / 39659
• FlyBaseID: FBgn0026323
• Length: 678
• Species: Drosophila melanogaster
• Sequence 2: NP_001382687.1
• Gene: Fer / 301737
• RGDID: 1306273
• Length: 823
• Species: Rattus norvegicus
• Alignment Length: 277
• Identity: 83/277 - (29%)
• Similarity: 132/277 - (47%)
• Gaps: 22/277 - (7%)

  Fly    14 VDFSEITLREKVGHGSYGVVCKAVWRDKL-VAVKEFFASAEQK---DIEKEVKQLSRVKHPNIIA 74
            ::..:::|.|.:|.|::|.|.|...:||. ||||.......|:   ...:|.|.|.:..||||:.
  Rat   559 LNHEDVSLGELLGKGNFGEVYKGTLKDKTPVAVKTCKEDLPQELKIKFLQEAKILKQYDHPNIVK 623

  Fly    75 LHGISSYQQATYLIMEFAEGGSLHNFLHGKVKPAYSLAHAMSWARQCAEGLAYLHAMTPKPLIHR 139
            |.|:.:.:|..|:|||...||...:||. |.|....|...:.::...|.|:.||..   |..|||
  Rat   624 LIGVCTQRQPVYIIMELVPGGDFLSFLR-KRKDELKLKQLVRFSLDVAAGMLYLEG---KNCIHR 684

  Fly   140 DVKPLNLLLTNKGRNLKICDFGTVADKSTMMTNNRG----SAAWMAPEVFEGSKYTEKCDIFSWA 200
            |:...|.|: .:...|||.|||....:...:.::.|    ...|.|||.....:|:.:.|::|:.
  Rat   685 DLAARNCLV-GENNTLKISDFGMSRQEDGGVYSSSGLKQIPIKWTAPEALNYGRYSSESDVWSFG 748

  Fly   201 IVLWEVLSRKQ-PFKGIDNAYTIQWKIYKGERPPLLTTCPKRIEDLMTACWKTVPEDRPSMQYIV 264
            |:|||..|... |:.|:.|....: ::.:|.|......||:.|..:|..||...||:||...
  Rat   749 ILLWETFSLGVCPYPGMTNQQARE-QVERGYRMSAPQNCPEEIFTIMMKCWDYKPENRPKFS--- 809

  Fly   265 GVMHEIVKDYTGADKAL 281
                ::.|:.|...|.:
  Rat   810 ----DLHKELTAIKKKI 822

Known Domains

Gene	Sequence	Domain	Region	External ID	Identity
Tak1	NP_524080.1	STKc_TAK1	25..275	CDD:270960	79/258 (31%)
Fer	NP_001382687.1	Important for interaction with membranes containing phosphoinositides. /evidence=ECO:0000250	1..300
		F-BAR_Fer	5..238	CDD:153370
		SH2_Fps_family	454..539	CDD:198224
		Protein Kinases, catalytic domain	567..817	CDD:473864	80/262 (31%)